66 statements
· 3 topics
· summaries given as host listed separately
Featured statements
▶Ep 1 · 3:00
I think the, the, the kids that show up with Crohn's disease for the first time with a perianal, perirectal abscess, uh, will often have non-colonic disease but small intestinal disease, and I'm not sure why it happens that way.
I would bet, I would bet that it's not a single one. I think most of those when you go in and drain a perianal abscess in a Crohn's disease, there are several fistulas there
Patients with severe ulcerative colitis who are emaciated, hypoalbuminemic, on steroids, and in poor nutritional status often require three-stage surgery: subtotal colectomy with end ileostomy, then subsequent J-pouch creation.
Endorectal dissection technique (similar to Hirschsprung surgery) can be performed safely for ulcerative colitis J-pouch even in relatively sick patients, as long as a diverting ileostomy is created.
clinicalChildren presenting with Crohn's disease for the first time with a perianal or perirectal abscess often have non-colonic small intestinal disease.↗
▶Ep 1 · 3:00
quoteI think the, the, the kids that show up with Crohn's disease for the first time with a perianal, perirectal abscess, uh, will often have non-colonic disease but small intestinal disease, and I'm not sure why it happens that way.↗
▶Ep 1 · 10:00
opinionPerianal abscesses in Crohn's disease are unlikely to heal without fecal diversion because bowel continuity slows healing.↗
▶Ep 1 · 11:00
clinicalModern TNF inhibitor drugs are effective at healing perianal disease in Crohn's, potentially allowing avoidance of fecal diversion in selected patients.↗
▶Ep 1 · 12:00
opinionPatients and parents would rather deal with a chronic perianal problem than manage a stoma.↗
▶Ep 1 · 12:00
quoteI think patients would rather deal with a chronic problem in their bottom than to deal and the parents deal with the stoma.↗
▶Ep 1 · 13:00
quoteI would bet, I would bet that it's not a single one. I think most of those when you go in and drain a perianal abscess in a Crohn's disease, there are several fistulas there↗
▶Ep 1 · 13:00
clinicalMost Crohn's perianal abscesses are not single; when draining a perianal abscess in Crohn's disease, there are usually several fistulas present.↗
▶Ep 1 · 14:00
quoteI'll tell you, Lou, if I had to deal with a perianal abscess in my butt. Or have her take care of a stoma from a terminal ileum, there's no question which would be easier to take care of.↗
▶Ep 1 · 14:00
opinionSetons are very effective for perianal fistulas and should be used more often in pediatric surgery than they currently are.↗
▶Ep 1 · 15:00
quoteIt's much less morbidity to go in and operate on 15 patients to take down and give them an ileostomy than to give 100 of them an ostomy that's my whole point.↗
▶Ep 1 · 15:00
opinionIt is less morbid to perform laparoscopic diversion in 15% of patients whose perianal disease fails to heal than to give 100% of patients an ostomy upfront.↗
▶Ep 1 · 16:00
clinicalCrohn's patients can develop peristomal fistulas as a complication of stoma creation.↗
▶Ep 1 · 17:00
clinicalCrohn's disease affects the entire GI tract as a chronic disorder, even when only one segment shows active stricturing disease.↗
▶Ep 1 · 18:00
quoteHave you ever seen a Crohn's perianal fistula that's a simple one? No.↗
▶Ep 1 · 19:00
clinicalA cutting seton requires 360-degree tension on tissue to actively divide it, whereas a non-cutting seton is placed loosely to allow drainage and gradual fibrosis without active cutting.↗
▶Ep 1 · 21:00
clinicalFor duodenal Crohn's strictures, endoscopic and fluoroscopic dilation combined with Remicade can be effective, making the stricture more pliable and allowing weight gain.↗
▶Ep 1 · 22:00
quoteI think that isolated TI disease we're going to find is a separate disease from here. I think that there's ulcerative colitistis, Crohn's, and then there's this other disease where it's isolated TI because it behaves very differently from perianal or diffuse Crohn's disease.↗
▶Ep 1 · 22:00
opinionIsolated terminal ileal Crohn's disease may be a separate disease entity from perianal or diffuse Crohn's disease because it behaves very differently, with prolonged remission after resection.↗
▶Ep 1 · 22:00
opinionPatients with isolated terminal ileal Crohn's disease should be considered for earlier resection before starting Remicade because of the favorable long-term outcomes after resection.↗
▶Ep 1 · 23:00
quoteI think some of these kids just, you know, it seems to me that the patients that we're getting now from the GI docs are in just horrible shape because they've, it's like we're the last resort. And we think of ulcerative colitis as a surgical disease. They think of it as a medical disease, so we're a failure. Surgery is failure to a GI doctor↗
▶Ep 1 · 23:00
opinionPediatric IBD patients referred for surgery are often in horrible nutritional shape because GI physicians view surgery as failure and carry patients on medical therapy for too long.↗
▶Ep 1 · 24:00
clinicalPatients with severe ulcerative colitis who are emaciated, hypoalbuminemic, on steroids, and in poor nutritional status often require three-stage surgery: subtotal colectomy with end ileostomy, then subsequent J-pouch creation.↗
▶Ep 1 · 25:00
clinicalPatients with ulcerative colitis recover incredibly fast after subtotal colectomy, much faster than after the subsequent J-pouch operation.↗
▶Ep 1 · 25:00
quotemy experience has been they get better incredibly fast after the subtotal, much faster than after the subsequent J pouch.↗
▶Ep 1 · 26:00
quotethe best they've ever, the best they ever look is when they have their stoma.↗
▶Ep 1 · 26:00
opinionThe best ulcerative colitis patients ever look is when they have their end ileostomy after subtotal colectomy, before J-pouch creation.↗
▶Ep 1 · 27:00
clinicalOngoing rectal bleeding from the rectal stump after subtotal colectomy for ulcerative colitis is rare but can be managed with local therapy.↗
▶Ep 1 · 28:00
clinicalEndorectal dissection technique (similar to Hirschsprung surgery) can be performed safely for ulcerative colitis J-pouch even in relatively sick patients, as long as a diverting ileostomy is created.↗
▶Ep 1 · 29:00
clinicalContinued bleeding from the rectal stump after subtotal colectomy for ulcerative colitis can force earlier-than-anticipated completion of the J-pouch procedure.↗
▶Ep 1 · 30:00
clinicalBetween stage 1 and stage 2 of ulcerative colitis surgery, patients often gain 20 to 30 pounds, which can make the subsequent operation technically harder.↗
Samir's statements about Necrotizing Enterocolitis4 statements
quoteI got to tell you I've got a love-hate relationship with stomas because I love the fact that sometimes they're they're useful to divert and be safe and stuff, but I hate them that you have to get them just right. You either get them too tight and they stricture or you get them too big and they prolapse↗
▶Ep 14 · 4:48
clinicalOstomy Cures in Europe has a titanium-based device prototype in clinical trials↗
▶Ep 14 · 4:48
clinicalOstomy Cures suspended all clinical trials because of COVID↗
▶Ep 14 · 4:48
clinicalThe Ostomy Cures device has a plastic lid that can be controlled to empty the bag or stoma↗
Samir's statements about Ulcerative Colitis31 statements
clinicalChildren presenting with Crohn's disease for the first time with a perianal or perirectal abscess often have non-colonic small intestinal disease.↗
▶Ep 3 · 3:00
quoteI think the, the, the kids that show up with Crohn's disease for the first time with a perianal, perirectal abscess, uh, will often have non-colonic disease but small intestinal disease, and I'm not sure why it happens that way.↗
▶Ep 3 · 10:00
opinionPerianal abscesses in Crohn's disease are unlikely to heal without fecal diversion because bowel continuity slows healing.↗
▶Ep 3 · 11:00
clinicalModern TNF inhibitor drugs are effective at healing perianal disease in Crohn's, potentially allowing avoidance of fecal diversion in selected patients.↗
▶Ep 3 · 12:00
quoteI think patients would rather deal with a chronic problem in their bottom than to deal and the parents deal with the stoma.↗
▶Ep 3 · 12:00
opinionPatients and parents would rather deal with a chronic perianal problem than manage a stoma.↗
▶Ep 3 · 13:00
quoteI would bet, I would bet that it's not a single one. I think most of those when you go in and drain a perianal abscess in a Crohn's disease, there are several fistulas there↗
▶Ep 3 · 13:00
clinicalMost Crohn's perianal abscesses are not single; when draining a perianal abscess in Crohn's disease, there are usually several fistulas present.↗
▶Ep 3 · 14:00
opinionSetons are very effective for perianal fistulas and should be used more often in pediatric surgery than they currently are.↗
▶Ep 3 · 14:00
quoteI'll tell you, Lou, if I had to deal with a perianal abscess in my butt. Or have her take care of a stoma from a terminal ileum, there's no question which would be easier to take care of.↗
▶Ep 3 · 15:00
quoteIt's much less morbidity to go in and operate on 15 patients to take down and give them an ileostomy than to give 100 of them an ostomy that's my whole point.↗
▶Ep 3 · 15:00
opinionIt is less morbid to perform laparoscopic diversion in 15% of patients whose perianal disease fails to heal than to give 100% of patients an ostomy upfront.↗
▶Ep 3 · 16:00
clinicalCrohn's patients can develop peristomal fistulas as a complication of stoma creation.↗
▶Ep 3 · 17:00
clinicalCrohn's disease affects the entire GI tract as a chronic disorder, even when only one segment shows active stricturing disease.↗
▶Ep 3 · 18:00
quoteHave you ever seen a Crohn's perianal fistula that's a simple one? No.↗
▶Ep 3 · 19:00
clinicalA cutting seton requires 360-degree tension on tissue to actively divide it, whereas a non-cutting seton is placed loosely to allow drainage and gradual fibrosis without active cutting.↗
▶Ep 3 · 21:00
clinicalFor duodenal Crohn's strictures, endoscopic and fluoroscopic dilation combined with Remicade can be effective, making the stricture more pliable and allowing weight gain.↗
▶Ep 3 · 22:00
opinionIsolated terminal ileal Crohn's disease may be a separate disease entity from perianal or diffuse Crohn's disease because it behaves very differently, with prolonged remission after resection.↗
▶Ep 3 · 22:00
opinionPatients with isolated terminal ileal Crohn's disease should be considered for earlier resection before starting Remicade because of the favorable long-term outcomes after resection.↗
▶Ep 3 · 22:00
quoteI think that isolated TI disease we're going to find is a separate disease from here. I think that there's ulcerative colitistis, Crohn's, and then there's this other disease where it's isolated TI because it behaves very differently from perianal or diffuse Crohn's disease.↗
▶Ep 3 · 23:00
quoteI think some of these kids just, you know, it seems to me that the patients that we're getting now from the GI docs are in just horrible shape because they've, it's like we're the last resort. And we think of ulcerative colitis as a surgical disease. They think of it as a medical disease, so we're a failure. Surgery is failure to a GI doctor↗
▶Ep 3 · 23:00
opinionPediatric IBD patients referred for surgery are often in horrible nutritional shape because GI physicians view surgery as failure and carry patients on medical therapy for too long.↗
▶Ep 3 · 24:00
clinicalPatients with severe ulcerative colitis who are emaciated, hypoalbuminemic, on steroids, and in poor nutritional status often require three-stage surgery: subtotal colectomy with end ileostomy, then subsequent J-pouch creation.↗
▶Ep 3 · 25:00
clinicalPatients with ulcerative colitis recover incredibly fast after subtotal colectomy, much faster than after the subsequent J-pouch operation.↗
▶Ep 3 · 25:00
quotemy experience has been they get better incredibly fast after the subtotal, much faster than after the subsequent J pouch.↗
▶Ep 3 · 26:00
opinionThe best ulcerative colitis patients ever look is when they have their end ileostomy after subtotal colectomy, before J-pouch creation.↗
▶Ep 3 · 26:00
quotethe best they've ever, the best they ever look is when they have their stoma.↗
▶Ep 3 · 27:00
clinicalOngoing rectal bleeding from the rectal stump after subtotal colectomy for ulcerative colitis is rare but can be managed with local therapy.↗
▶Ep 3 · 28:00
clinicalEndorectal dissection technique (similar to Hirschsprung surgery) can be performed safely for ulcerative colitis J-pouch even in relatively sick patients, as long as a diverting ileostomy is created.↗
▶Ep 3 · 29:00
clinicalContinued bleeding from the rectal stump after subtotal colectomy for ulcerative colitis can force earlier-than-anticipated completion of the J-pouch procedure.↗
▶Ep 3 · 30:00
clinicalBetween stage 1 and stage 2 of ulcerative colitis surgery, patients often gain 20 to 30 pounds, which can make the subsequent operation technically harder.↗
Summaries Samir gave as host
· 20 summaries
Recaps of other experts' statements, not Samir's own clinical position.
Summaries Samir gave as host · Crohn's Disease10 summaries
host summarySamir Pandya summarizing a resource: In a review study published recently, CT enterography is more accurate than MR enterography for Crohn's disease, though institutional radiologist expertise determines which modality performs better in practice.↗
▶Ep 1 · 4:00
host summarySamir Pandya summarizing a resource: Contrast-enhanced ultrasound is only available for clinical use in Europe at present and has not been approved by the FDA.↗
▶Ep 1 · 4:00
host summarySamir Pandya summarizing a resource: Contrast-enhanced ultrasound has sensitivity and specificity as high as 100% for Crohn's disease in previously undiagnosed patients, and above 95% in patients with known diagnosis, according to the Peloda study published in Pediatrics 2013.↗
▶Ep 1 · 5:00
host summarySamir Pandya summarizing a resource: In Europe, ultrasound is the first-line imaging choice for Crohn's disease, followed by MR or CT enterography, whereas in the US, MR/CT enterography is first-line.↗
▶Ep 1 · 6:00
host summarySamir Pandya summarizing a resource: MR enterography provides information about the chronicity of Crohn's disease strictures, helping determine whether a stricture is chronic and fibrotic (unlikely to resolve with medication) or potentially responsive to medical therapy.↗
▶Ep 1 · 18:00
host summarySamir Pandya summarizing a resource: Rectal advancement flap for Crohn's perianal fistula is only appropriate in the setting of no active proctitis, and results diminish with time.↗
▶Ep 1 · 20:00
host summarySamir Pandya summarizing a resource: Even with permanent fecal diversion, as high as 40% of Crohn's patients have recalcitrant perianal disease as they reach adulthood.↗
▶Ep 1 · 22:00
host summarySamir Pandya summarizing a resource: Isolated ileocecal Crohn's disease in teenagers can have recurrence-free intervals as long as 10 to 15 years after resection, allowing symptom-free passage through puberty into adulthood.↗
▶Ep 1 · 28:36
host summarySamir Pandya summarizing a resource: At 2 years follow-up, there is hardly any difference in bowel frequency between straight ileoanal anastomosis and J-pouch (10 cm J-pouches) for ulcerative colitis, based on a series of 120-130 straight and 110-115 J-pouch patients.↗
▶Ep 1 · 28:36
host summarySamir Pandya summarizing a resource: If a patient has received infliximab within the last 6 weeks before surgery for ulcerative colitis, there is evidence (both adult and pediatric) that a three-stage approach should probably be used due to increased complication risk.↗
Summaries Samir gave as host · Ulcerative Colitis10 summaries
host summarySamir Pandya summarizing a resource: In a review study published recently, CT enterography is more accurate than MR enterography for Crohn's disease, though institutional radiologist expertise determines which modality performs better in practice.↗
▶Ep 3 · 4:00
host summarySamir Pandya summarizing a resource: Contrast-enhanced ultrasound has sensitivity and specificity as high as 100% for Crohn's disease in previously undiagnosed patients, and above 95% in patients with known diagnosis, according to the Peloda study published in Pediatrics 2013.↗
▶Ep 3 · 4:00
host summarySamir Pandya summarizing a resource: Contrast-enhanced ultrasound is only available for clinical use in Europe at present and has not been approved by the FDA.↗
▶Ep 3 · 5:00
host summarySamir Pandya summarizing a resource: In Europe, ultrasound is the first-line imaging choice for Crohn's disease, followed by MR or CT enterography, whereas in the US, MR/CT enterography is first-line.↗
▶Ep 3 · 6:00
host summarySamir Pandya summarizing a resource: MR enterography provides information about the chronicity of Crohn's disease strictures, helping determine whether a stricture is chronic and fibrotic (unlikely to resolve with medication) or potentially responsive to medical therapy.↗
▶Ep 3 · 18:00
host summarySamir Pandya summarizing a resource: Rectal advancement flap for Crohn's perianal fistula is only appropriate in the setting of no active proctitis, and results diminish with time.↗
▶Ep 3 · 20:00
host summarySamir Pandya summarizing a resource: Even with permanent fecal diversion, as high as 40% of Crohn's patients have recalcitrant perianal disease as they reach adulthood.↗
▶Ep 3 · 22:00
host summarySamir Pandya summarizing a resource: Isolated ileocecal Crohn's disease in teenagers can have recurrence-free intervals as long as 10 to 15 years after resection, allowing symptom-free passage through puberty into adulthood.↗
▶Ep 3 · 28:36
host summarySamir Pandya summarizing a resource: If a patient has received infliximab within the last 6 weeks before surgery for ulcerative colitis, there is evidence (both adult and pediatric) that a three-stage approach should probably be used due to increased complication risk.↗
▶Ep 3 · 28:36
host summarySamir Pandya summarizing a resource: At 2 years follow-up, there is hardly any difference in bowel frequency between straight ileoanal anastomosis and J-pouch (10 cm J-pouches) for ulcerative colitis, based on a series of 120-130 straight and 110-115 J-pouch patients.↗
