Effects of Growth Factor Application on Germ Cell Architecture and Oxidative Stress Handling in a Rat Model of Testicular Torsion–detorsion

Abstract

Testicular torsion is a surgical emergency in paediatric population, in which delayed intervention often leads to irreversible ischaemic injury. Oxidative stress plays a key role in testicular damage. Although several experimental therapies have been explored, the effect of local growth hormone (GH) application needs to be further defined. This study evaluated the impact of local GH on testicular morphology and oxidative stress parameters following torsion–detorsion in a rat model.

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