Perinatal prognostic factors of recurrence or functional sequelae in neonatal sacrococcygeal teratoma, and implications for prenatal counselling: a multicenter retrospective study.

Abstract

With an estimated prevalence of 1/40,000-1/10,000 births and a sex ratio of four female for one male [1–3], sacrococcygeal teratoma (SCT) is the most frequent tumor encountered in the fetus and neonate. SCT is an archetypical example of the links between congenital malformations and tumorigenesis in children. It is defined by the presence, in the sacrococcygeal region, of at least two tissues originating from the three primitive embryonic layers, with possible various degrees of maturation [4].

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