From
Dr. Amr Moursi
Neuromodulation vs. Neuroablation | Functional Neurosurgery Explained – Episode 3
With Dr. Amr Moursi
Part of
Parkinson's Disease 7 items
Chapter 1 of 1 · Fundamentals
Introduction
Series introduction and episode overview
Expert statements on this page
No expert statements were drawn from this page.
Host summaries · secondary, not cited in answers
Educational content from recorded physician discussions — not medical advice. Talk to your (or your child's) care team about your situation.
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What the experts said
Parkinson's disease is a circuit disorder, not just a dopamine deficiency.
The subthalamic nucleus becomes overactive in Parkinson's disease despite being structurally intact.
Irreversibility was the fatal limitation of thalamotomy and pallidotomy.
Benabid discovered in Grenoble in 1987 that high-frequency stimulation could replicate the effects of ablative lesions reversibly, shifting the entire question of surgery.
Adaptive closed-loop DBS represents the future of the field.
The first thalamotomies for Parkinson's disease were performed in the 1950s.