Impact of the relationship between renal pedicles and tumors on surgical outcomes for non-high-risk abdominal neuroblastoma
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In brief
In brief
This retrospective study examines how tumor proximity to renal pedicles affects surgical outcomes in 27 non-high-risk abdominal neuroblastoma cases. Tumors encasing renal pedicles carried the highest risk of renal complications, including concurrent nephrectomy and post-operative atrophy, followed by tumors in contact with pedicles.
- Neuroblastoma tumors encasing renal pedicles carry highest risk of renal complications including nephrectomy and post-op atrophy.
- Preoperative imaging classification (encasing vs. contact vs. separated) predicts surgical renal complication risk in abdominal neuroblastoma.
- Even tumors in contact with renal pedicles show measurable renal complication risk compared to separated tumors.
- Delayed surgery may allow tumor regression away from renal pedicles, reducing encasement cases from 11 to 5 in this cohort.
Written by the GCMD Library team from the article.
Abstract
Purpose
To assess the impact of the relationship between renal pedicles and tumors on surgical outcomes in patients with non-high-risk abdominal neuroblastoma.
Methods
We retrospectively analyzed cases of neuroblastoma without metastasis treated at our hospital between March 2002 and December 2023. Cases in which surgical resection was performed were divided into three groups according to imaging findings at the time of diagnosis and before surgery: Group E (tumor encasing renal pedicles), Group C (tumor in contact with renal pedicles), and Group S (tumor separated from renal pedicles).
Results
Among 256 neuroblastoma cases diagnosed during the study period, 27 non-high-risk cases that underwent surgery for partial abdominal tumor resection or greater were included. The numbers of cases in the S group, C group, and E group, respectively, were 7, 9, and 11 at diagnosis, and 8, 14, and 5 before surgery. Renal complications (combined concurrent renal resection and post-operative renal atrophy) were seen in five E group cases at the time of diagnosis, and two C group cases and three E group cases preoperatively.
Conclusion
In non-high-risk abdominal neuroblastomas, tumors encased in the renal pedicles have the highest risk of renal complications, followed by tumors in contact with the renal pedicles.