Fluorescence-guided lymph node sampling is feasible during up-front or delayed nephrectomy for Wilms tumor.

Background: Lymph node sampling is critical to surgical staging in Wilms tumor; failure to sample lymph nodes is associated with under-staging and an increased incidence of local relapse. However, no standard lymphatic mapping method is currently being utilized for Wilms tumor to aid identification of regional draining lymph nodes. Herein, we describe the use of fluorescence-guided lymphatic mapping for Wilms tumor.Materials and methods: Two tertiary level referral centers independently began indocyanine green (ICG) fluorescence-guided nodal mapping.