Ovarian tumors in children: how common are lesion recurrence and metachronous disease? A UK CCLG Surgeons Cancer Group nationwide study
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In brief
In brief
UK nationwide study examined recurrence and metachronous disease rates in pediatric ovarian tumors, primarily mature teratomas. Despite excellent prognosis after complete resection, reported recurrence varies widely (2.5-23%), yet follow-up guidelines remain inconsistent across centers.
Written by the GCMD Library team from the article.
Background
Ovarian tumors in children are rare, mature teratoma being the most common histological entity. Robust guidelines to aid patient follow-up after resection are distinctly lacking. Although mature teratoma has a very good prognosis following complete resection, small studies have reported the occurrence of metachronous disease and recurrence to a variable degree (2.5–23% of patients). Nevertheless, there are surgeons who recommend no follow-up is required for these children after primary tumor resection. We investigated the incidence of (i) recurrence and (ii) metachronous disease in pediatric patients following ovarian tumor resection.
Methods
Retrospective multicenter study amongst UK pediatric surgical oncology centers. Females