Surgical management of locally-advanced and metastatic hepatoblastoma
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In brief
In brief
This review examines surgical strategies for advanced-stage hepatoblastoma, including locally invasive tumors and metastatic disease. The authors discuss complex hepatic resections versus liver transplantation for primary tumors involving multiple lobes or major vessels, and address management of pulmonary metastases.
Written by the GCMD Library team from the article.
Publication date: Available online 13 November 2019
Source: Seminars in Pediatric Surgery
Author(s): Charissa M. Lake, Gregory M. Tiao, Alexander J. Bondoc
ABSTRACT
Advanced stage hepatoblastoma, including both locally advanced primary tumors as well as metastatic disease, poses unique clinical challenges. Despite substantial advances in chemotherapeutics, surgical extirpation remains the mainstay of cure for this tumor. Locally advanced tumors that involve multiple hepatic lobes and/or invade significant vascular structures can be managed either by complex hepatic resections or liver transplantation. We review the indications, roles, and outcomes of these surgical approaches as well as those for the resection of pulmonary metastases.