Dr. Jeffrey Ponsky · Peroral endoscopic myotomy (POEM) leads to similar results in patients with and without prior endoscopic or surgical therapy
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Article1 min read·Published Jul 2026

Peroral endoscopic myotomy (POEM) leads to similar results in patients with and without prior endoscopic or surgical therapy

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Article · Jul 2026 · 1 min read

In brief

In brief

This study demonstrates that peroral endoscopic myotomy (POEM) achieves comparable clinical outcomes in achalasia patients regardless of prior treatment history. Patients with previous endoscopic or surgical interventions showed similar operative times, GERD symptom scores, and quality of life measures to treatment-naïve patients, supporting POEM as an effective option for both primary and salvage therapy.

Written by the GCMD Library team from the article.

Jeffrey Ponsky

We found favorable outcomes following POEM in patients who have had prior endoscopic or surgical treatments for achalasia, as well as for patients without prior intervention. There were no significant differences between these two groups with regards to operative times, GERD-HRQL scores, and mental …

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