The majority of cases were class two clean contaminated cases, which is more in keeping with the literature in terms of adult SSI reduction in use of CHG antisepsis.
PAPS - Optimizing skin antisepsis for neonatal surgery - Sophie Carr
▶Ep 3 · 0:00
quoteSurgical site infections are a costly, yet modifiable source morbidity, particularly within the neonatal population.↗
▶Ep 3 · 0:00
quoteA total of 50 patients were included, none of which experienced adverse skin prep outcomes.↗
▶Ep 3 · 0:00
clinicalSurgical site infections are a costly, yet modifiable source of morbidity, particularly within the neonatal population.↗
▶Ep 3 · 0:00
epidemiologicalEquivalent data does not yet exist for the neonatal surgical population comparing CHG-IPA to povidone iodine.↗
▶Ep 3 · 0:00
clinicalThe protocol inclusion was limited to general surgery patients with 34 weeks post conceptual age and 1500 grams as the lower age and weight limits.↗
▶Ep 3 · 0:00
clinicalEither 2% or 0.5% CHG solution was used based on age cutoffs.↗
▶Ep 3 · 0:00
clinicalSkin integrity was assessed using a validated tool called the neonatal skin condition score.↗
▶Ep 3 · 0:00
clinicalImplementation of the protocol occurred in February 2020.↗
▶Ep 3 · 0:00
clinicalA total of 50 patients were included, none of which experienced adverse skin prep outcomes.↗
▶Ep 3 · 0:00
epidemiological8% of patients in the CHG cohort developed SSIs within the 30-day post-op period compared to 14% in the matched retrospective povidone cohort.↗
▶Ep 3 · 0:00
epidemiologicalA comparison of SSI rates between the CHG versus PI cohort revealed no significant difference.↗
▶Ep 3 · 4:43
clinicalThe protocol was largely modeled off the McGill protocol used in Quebec, Canada, which used a lower age cutoff of 28 weeks gestational age with a lower weight cutoff of 1000 grams.↗
▶Ep 3 · 4:43
clinicalThe majority of cases were class two clean contaminated cases, which is more in keeping with the literature in terms of adult SSI reduction in use of CHG antisepsis.↗
▶Ep 3 · 4:43
clinicalThe project was conducted in conjunction with initiatives including optimizing antibiotic prophylaxis, using adherent draping, and for class two clean contaminated cases, using a clean closure bundle including changing gloves prior to closure.↗
▶Ep 3 · 8:26
clinicalThe protocol applied to all general surgery cases that did not have any open exposed mucosa and in which the patient was not allergic to CHG or IPA.↗
▶Ep 3 · 8:26
epidemiologicalThe decrease in SSI was not statistically significant.↗
PAPS Best of the Best Winner
▶Ep 4 · 1:55
quoteSurgical site infections are a costly yet modifiable source of morbidity, particularly within the neonatal population.↗
▶Ep 4 · 1:55
clinicalSurgical site infections are a costly yet modifiable source of morbidity, particularly within the neonatal population.↗
▶Ep 4 · 2:28
epidemiologicalEquivalent data does not yet exist for the neonatal surgical population for CHG versus povidone antisepsis.↗
▶Ep 4 · 3:30
clinicalThe neonatal skin antisepsis protocol included lower limits of 34 weeks post-conception age and 1500 grams weight, limited to general surgery patients only.↗
▶Ep 4 · 3:45
clinicalThe protocol used either 2% or 0.5% CHG based on age cutoffs.↗
▶Ep 4 · 3:52
clinicalSkin integrity was assessed using a validated tool called the neonatal skin condition score.↗
▶Ep 4 · 4:15
clinicalImplementation of the protocol occurred in February 2020.↗
▶Ep 4 · 4:25
quoteA total of 50 patients were included, none of which experienced adverse skin prep outcomes.↗
▶Ep 4 · 4:25
clinicalA total of 50 patients were included in the protocol, none of which experienced adverse skin prep outcomes.↗
▶Ep 4 · 4:35
epidemiological8% of patients on the CHG protocol developed SSIs within the 30-day post-op period compared to 14% in the matched retrospective povidone cohort.↗
▶Ep 4 · 4:48
epidemiologicalA comparison of SSI rates between the CHG versus povidone cohort revealed no significant difference.↗
▶Ep 4 · 6:20
clinicalThe majority of cases were class two clean-contaminated cases.↗
▶Ep 4 · 7:00
clinicalThe protocol was largely modeled off the McGill protocol used in Quebec, Canada, which used a lower age cutoff of 28 weeks gestational age with a lower weight cutoff of 1,000 grams.↗
▶Ep 4 · 8:00
clinicalThe project was conducted in conjunction with multiple SSI reduction initiatives including optimizing antibiotic prophylaxis, using adherent draping, and implementing a clean closure bundle for class two clean-contaminated cases.↗
▶Ep 4 · 8:25
clinicalThe clean closure bundle included changing gloves prior to closure.↗
▶Ep 4 · 9:43
epidemiologicalThe decrease in SSI rate from 14% to 8% was not statistically significant.↗
▶Ep 4 · 9:55
clinicalThe protocol was used for all general surgery cases that did not have any open exposed mucosa and in which the patient was not allergic to CHG or IPA.↗
Summaries Sophie gave as host
· 10 summaries
Recaps of other experts' statements, not Sophie's own clinical position.
Summaries Sophie gave as host · Surgical Site Infections10 summaries
PAPS - Optimizing skin antisepsis for neonatal surgery - Sophie Carr
▶Ep 3 · 0:00
host summarySophie Carr summarizes what Dr. Rebecca Rentea said: Although commonly used within the neonatal population, current product labeling discourages CHG IPA antisepsis in infants under two months of age, as there is limited safety data and concerns around adverse effects, particularly skin injuries.↗
▶Ep 3 · 0:00
host summarySophie Carr summarizes what Dr. Rebecca Rentea said: A growing body of evidence in adults suggests that chlorhexidine gluconate and isopropyl alcohol provide superior protection against SSIs than povidone iodine.↗
▶Ep 3 · 0:00
host summarySophie Carr summarizes what Dr. Rebecca Rentea said: CHG antisepsis is commonly used for invasive non-surgical procedures in NICUs and for prevention of newborn nosocomial infections in developing countries.↗
▶Ep 3 · 0:00
host summarySophie Carr summarizes what Dr. Rebecca Rentea said: Current product labeling discourages CHG IPA antisepsis in infants under two months of age due to limited safety data and concerns around adverse effects, particularly skin injuries.↗
▶Ep 3 · 4:43
host summarySophie Carr summarizes what Dr. Rebecca Rentea said: The primary adverse concern is skin reactions with less than 28 weeks gestational age being the primary population affected by those in the literature.↗
PAPS Best of the Best Winner
▶Ep 4 · 2:15
host summarySophie Carr summarizes what Dr. Rebecca Rentea said: A growing body of evidence in adults suggests that chlorhexidine gluconate and isopropyl alcohol provide superior protection against SSIs than povidone.↗
▶Ep 4 · 2:35
host summarySophie Carr summarizes what Dr. Rebecca Rentea said: CHG antisepsis is commonly used for invasive non-surgical procedures in NICUs and for prevention of newborn nosocomial infections in developing countries.↗
▶Ep 4 · 2:48
host summarySophie Carr summarizes what Dr. Rebecca Rentea said: Current product labeling discourages CHG-IPA antisepsis in infants under two months of age due to limited safety data and concerns around adverse effects, particularly skin injuries.↗
▶Ep 4 · 2:48
host summarySophie Carr summarizes what Dr. Rebecca Rentea said: Although commonly used within the neonatal population, current product labeling discourages CHG IPA antisepsis in infants under two months of age, as there is limited safety data and concerns around adverse effects, particularly skin injuries.↗
▶Ep 4 · 7:45
host summarySophie Carr summarizes what Dr. Rebecca Rentea said: Less than 28 weeks gestational age is the primary population affected by adverse skin reactions in the literature.↗
