We published quite a few years ago on infants that were coming to surgery for other matters who later turned out to have biliary atresia in the first week of life. They all had normal livers. So you can't really diagnose those early ones on liver biopsy, that's certainly true.
The key point about the biopsy is really to not go to theater to not have a general anesthetic and to not undergo an invasive investigation and to exclude all those I'll put it medical conditions that that sort of mimic biliary atresia.
Stem cells can be made from blood samples of children born with abnormal kidneys to grow organoids in culture that reproduce the disease in a dish, allowing researchers to look for druggable targets.
The Newcastle series is a pushback series which extols relatively conventional open surgery and begs the question as to what role lengthening procedures have in those with long gaps.
quoteThe key point about the biopsy is really to not go to theater to not have a general anesthetic and to not undergo an invasive investigation and to exclude all those I'll put it medical conditions that that sort of mimic biliary atresia.↗
▶Ep 8 · 22:18
clinicalInfants coming to surgery for other matters who later turned out to have biliary atresia in the first week of life all had normal livers, so you can't diagnose early biliary atresia on liver biopsy↗
▶Ep 8 · 22:18
quoteWe published quite a few years ago on infants that were coming to surgery for other matters who later turned out to have biliary atresia in the first week of life. They all had normal livers. So you can't really diagnose those early ones on liver biopsy, that's certainly true.↗
▶Ep 8 · 23:08
clinicalLiver histology looking at inflammation and fibrosis has not shown great discrimination for prognosis in babies coming to surgery before 100 days↗
▶Ep 8 · 24:57
clinicalThe key differential for a prenatally detected cyst is between cystic biliary atresia and a choledochal cyst↗
▶Ep 8 · 25:51
clinicalIf the baby is not jaundiced and not raising conjugated bilirubin, then it's not cystic biliary atresia and you can wait to do the laparotomy↗
Biliary Atresia Part I
▶Ep 13 · 6:56
clinicalThe key diagnostic finding is conjugated hyperbilirubinemia.↗
▶Ep 13 · 6:56
quoteThe key thing is to show that you've got a conjugated hyperbilirubinemia. And if you've done that, then all else flows.↗
▶Ep 13 · 6:56
quoteThe key thing is to show that you've got a conjugated hyperbilirubinemia. And if you've done that, then all else flows.↗
▶Ep 13 · 6:56
clinicalThe key diagnostic finding is conjugated hyperbilirubinemia.↗
▶Ep 13 · 8:39
clinicalUltrasound separates out other surgical issues including inspissated bile syndrome and spontaneous perforation of bile ducts, which should have ultrasound-positive features.↗
▶Ep 13 · 8:39
clinicalUltrasound separates out other surgical issues including inspissated bile syndrome and spontaneous perforation of bile ducts, which should have ultrasound-positive features.↗
▶Ep 13 · 8:39
opinionThe triangular cord sign on ultrasound is not particularly discriminatory for biliary atresia.↗
▶Ep 13 · 8:39
opinionThe triangular cord sign on ultrasound is not particularly discriminatory for biliary atresia.↗
▶Ep 13 · 10:41
clinicalExperienced pathologists can diagnose biliary atresia from percutaneous liver biopsy in almost 90% of cases.↗
▶Ep 13 · 10:41
clinicalExperienced pathologists can diagnose biliary atresia from percutaneous liver biopsy in almost 90% of cases.↗
▶Ep 13 · 15:17
clinicalKing's College Hospital uses ERCP for approximately 10% of biliary atresia cases when biopsy findings are equivocal.↗
▶Ep 13 · 15:17
clinicalKing's College Hospital uses ERCP for approximately 10% of biliary atresia cases when biopsy findings are equivocal.↗
▶Ep 13 · 15:29
quoteThey're not made in America. Don't worry about that. It's a Japanese scope.↗
▶Ep 13 · 15:29
quoteThey're not made in America. Don't worry about that. It's a Japanese scope.↗
▶Ep 13 · 15:47
quoteThe other pathognomonic finding for biliary atresia, as opposed to some of the other obstructive processes, is you'll see bile duct plugs in those bile ducts that are proliferating.↗
▶Ep 13 · 15:47
clinicalHistologic findings diagnostic of biliary atresia include ductular proliferation, small cell infiltrate, and bile duct plugs in proliferating bile ducts.↗
▶Ep 13 · 15:47
clinicalBy 50 days of age, all histologic features of biliary atresia should be established on biopsy, whereas earlier biopsies (10-20 days) may not show consistent diagnostic findings.↗
▶Ep 13 · 15:47
quoteThe other pathognomonic finding for biliary atresia, as opposed to some of the other obstructive processes, is you'll see bile duct plugs in those bile ducts that are proliferating.↗
▶Ep 13 · 15:47
clinicalHistologic findings diagnostic of biliary atresia include ductular proliferation, small cell infiltrate, and bile duct plugs in proliferating bile ducts.↗
▶Ep 13 · 15:47
clinicalBy 50 days of age, all histologic features of biliary atresia should be established on biopsy, whereas earlier biopsies (10-20 days) may not show consistent diagnostic findings.↗
▶Ep 13 · 19:17
quoteThis is one of the last remaining examples of a maximally invasive operation.↗
▶Ep 13 · 19:17
quoteThis is one of the last remaining examples of a maximally invasive operation.↗
▶Ep 13 · 28:21
clinicalCoring into the liver creates an unstable interface that has never achieved good results in the literature, as biliary ductules that transgress simply scar over.↗
▶Ep 13 · 28:21
quoteIt's a beautiful thing to see, the surgical plane. You can almost strip it off. And the idea is there's nothing left.↗
▶Ep 13 · 28:21
quoteAny kind of biliary ductules that transgress that just simply scar over. I've never seen any kind of coring of the liver that's achieved anything in the literature.↗
▶Ep 13 · 28:21
quoteAny kind of biliary ductules that transgress that just simply scar over. I've never seen any kind of coring of the liver that's achieved anything in the literature.↗
▶Ep 13 · 28:21
clinicalCoring into the liver creates an unstable interface that has never achieved good results in the literature, as biliary ductules that transgress simply scar over.↗
▶Ep 13 · 28:21
quoteIt's a beautiful thing to see, the surgical plane. You can almost strip it off. And the idea is there's nothing left.↗
▶Ep 13 · 29:48
clinicalStandard Roux limb length for Kasai portoenterostomy is 40 centimeters, though Cincinnati uses 35-40 cm and measures with silk suture to 45 cm.↗
▶Ep 13 · 29:48
clinicalStandard Roux limb length for Kasai portoenterostomy is 40 centimeters, though Cincinnati uses 35-40 cm and measures with silk suture to 45 cm.↗
Biliary Atresia Part II
▶Ep 14 · 7:19
epidemiologicalSTART trial subset analysis for patients <70 days old: placebo arm 57% jaundice clearance, steroid arm 72% clearance—difference not statistically significant due to insufficient numbers (type 2 error)↗
▶Ep 14 · 7:19
epidemiologicalSTART trial subset analysis for patients <70 days old: placebo arm 57% jaundice clearance, steroid arm 72% clearance—difference not statistically significant due to insufficient numbers (type 2 error)↗
▶Ep 14 · 9:56
epidemiologicalKing's College initial low-dose steroid trial (2mg/kg/day prednisone): no difference in jaundice clearance between groups, but statistically significant lower bilirubin at one month in steroid group↗
▶Ep 14 · 9:56
epidemiologicalKing's College high-dose steroid protocol (5mg/kg/day): 67% jaundice clearance vs 52% in controls, difference reached statistical significance with larger numbers↗
▶Ep 14 · 9:56
epidemiologicalKing's College initial low-dose steroid trial (2mg/kg/day prednisone): no difference in jaundice clearance between groups, but statistically significant lower bilirubin at one month in steroid group↗
▶Ep 14 · 9:56
epidemiologicalKing's College high-dose steroid protocol (5mg/kg/day): 67% jaundice clearance vs 52% in controls, difference reached statistical significance with larger numbers↗
▶Ep 14 · 12:02
clinicalKing's College current protocol: 5mg/kg/day prednisone starting day 4 post-op when oral feeds begin↗
▶Ep 14 · 12:02
clinicalKing's College current protocol: 5mg/kg/day prednisone starting day 4 post-op when oral feeds begin↗
▶Ep 14 · 17:35
clinicalGI bleeding is a potential steroid complication; King's College always gives ranitidine with steroids, which may not have been standard in START trial↗
▶Ep 14 · 17:35
clinicalGI bleeding is a potential steroid complication; King's College always gives ranitidine with steroids, which may not have been standard in START trial↗
▶Ep 14 · 19:34
clinicalKing's College antibiotic protocol: IV tazocin-gentamicin for 5 days, then oral cephalosporin for 1 month↗
▶Ep 14 · 19:34
clinicalKing's College antibiotic protocol: IV tazocin-gentamicin for 5 days, then oral cephalosporin for 1 month↗
▶Ep 14 · 21:20
epidemiologicalKing's College data from 2001: 100+ day Kasai patients achieved approximately 40% five-year native liver survival↗
▶Ep 14 · 21:20
clinicalFor patients presenting at 100+ days with cirrhosis on ultrasound (heterogeneous surface, ascites), consider primary transplant rather than Kasai; primary transplant rate in England/Wales is approximately 5%↗
▶Ep 14 · 21:20
epidemiologicalKing's College data from 2001: 100+ day Kasai patients achieved approximately 40% five-year native liver survival↗
▶Ep 14 · 21:20
clinicalFor patients presenting at 100+ days with cirrhosis on ultrasound (heterogeneous surface, ascites), consider primary transplant rather than Kasai; primary transplant rate in England/Wales is approximately 5%↗
▶Ep 14 · 25:41
epidemiologicalKing's College data with high-dose steroids: 100% of patients who underwent Kasai before 30 days of age cleared their jaundice↗
▶Ep 14 · 25:41
epidemiologicalKing's College data with high-dose steroids: 100% of patients who underwent Kasai before 30 days of age cleared their jaundice↗
▶Ep 14 · 28:16
clinicalKing's College does not use steroids for cholangitis treatment and does not perform early revision Kasai↗
▶Ep 14 · 28:16
clinicalKing's College does not use steroids for cholangitis treatment and does not perform early revision Kasai↗
▶Ep 14 · 32:54
epidemiologicalCMV IgM-positive biliary atresia represents approximately 10% of cases in Western Europe and North America; prevalence higher in China and Japan↗
▶Ep 14 · 32:54
epidemiologicalCMV IgM-positive biliary atresia represents approximately 10% of cases in Western Europe and North America; prevalence higher in China and Japan↗
▶Ep 14 · 34:15
quoteIn the last analysis, we cleared jaunice in seven out of nine of them, which is about 70 odd percent. And that was a dramatic difference from what we'd experienced previously.↗
▶Ep 14 · 34:15
clinicalCMV PCR levels in biliary atresia show inverse relationship with age and AST levels; highest viral loads in younger babies, suggesting body clears virus over time↗
▶Ep 14 · 34:15
quoteIn the last analysis, we cleared jaunice in seven out of nine of them, which is about 70 odd percent. And that was a dramatic difference from what we'd experienced previously.↗
▶Ep 14 · 34:15
clinicalKing's College prospective antiviral treatment (valganciclovir): 7 of 9 (approximately 78%) CMV-positive patients cleared jaundice, dramatic improvement from historical <10%↗
▶Ep 14 · 34:15
quoteWhen we separated out the CMV positive and compared it with the CMV negative as a control, there was a dramatic difference, not only in their clinical characteristics, because the CMV positive were older by the time of their Kisai operation, but also the histology was different. And their outcomes were very different.↗
▶Ep 14 · 34:15
clinicalKing's College prospective antiviral treatment (valganciclovir): 7 of 9 (approximately 78%) CMV-positive patients cleared jaundice, dramatic improvement from historical <10%↗
▶Ep 14 · 34:15
epidemiologicalKing's College retrospective data (2010-11): CMV IgM-positive patients were older at Kasai, had different histology, and cleared jaundice in less than 10% of cases without antiviral treatment↗
▶Ep 14 · 34:15
epidemiologicalKing's College retrospective data (2010-11): CMV IgM-positive patients were older at Kasai, had different histology, and cleared jaundice in less than 10% of cases without antiviral treatment↗
▶Ep 14 · 34:15
clinicalCMV PCR levels in biliary atresia show inverse relationship with age and AST levels; highest viral loads in younger babies, suggesting body clears virus over time↗
▶Ep 14 · 34:15
quoteWhen we separated out the CMV positive and compared it with the CMV negative as a control, there was a dramatic difference, not only in their clinical characteristics, because the CMV positive were older by the time of their Kisai operation, but also the histology was different. And their outcomes were very different.↗
▶Ep 14 · 38:22
clinicalIncreasing proportion of biliary atresia patients require transplant despite modest bilirubin elevation due to progressive fibrosis and portal hypertension complications↗
▶Ep 14 · 38:22
clinicalIncreasing proportion of biliary atresia patients require transplant despite modest bilirubin elevation due to progressive fibrosis and portal hypertension complications↗
▶Ep 14 · 38:22
epidemiologicalKing's College colchicine trial (1970s-80s) for liver fibrosis showed no difference in long-term fibrosis levels or clinical outcomes between treatment and placebo groups↗
▶Ep 14 · 38:22
epidemiologicalKing's College colchicine trial (1970s-80s) for liver fibrosis showed no difference in long-term fibrosis levels or clinical outcomes between treatment and placebo groups↗
Mark's statements about Colorectal / ARM & Hirschsprung4 statements
Journal of Pediatric Surgery Article Review: February 2023, BAPS issue
▶Ep 135 · 3:38
clinicalThe Centre in Rocklaw has become the referral center for esophageal atresia and long gap esophageal atresia cases from the whole of Poland↗
▶Ep 135 · 6:35
opinionThe Sheffield study represents real life surgical reporting and reflects overall management of Hirschsprung's disease within the UK↗
▶Ep 135 · 9:04
clinicalThe Tanzania study used trained carers to direct the method of cleansing, concentrating on areas known to harbor commensal and pathogenic bacteria↗
▶Ep 135 · 11:04
opinionThe Tanzania soap bathing trial was well designed, analyzed in substantial detail, and has implications for low to middle income countries where surgical site infections are a major problem↗
Mark's statements about Complicated Appendicitis2 statements
Journal of Pediatric Surgery Article Review: Q1 (Jan-Mar) 2024
▶Ep 4 · 7:32
quoteNevertheless, this is definitely a pushback series which extols relatively conventional open surgery, of course. It really, it really does beg the question as to what role and they would say, if any, er lengthening procedures have in those with er with long gaps.↗
▶Ep 4 · 7:32
opinionThe Newcastle series is a pushback series which extols relatively conventional open surgery and begs the question as to what role lengthening procedures have in those with long gaps.↗
Mark's statements about Esophageal Atresia6 statements
Journal of Pediatric Surgery Article Review: February 2023, BAPS issue
▶Ep 23 · 3:38
clinicalThe Centre in Rocklaw has become the referral center for esophageal atresia and long gap esophageal atresia cases from the whole of Poland↗
▶Ep 23 · 6:35
opinionThe Sheffield study represents real life surgical reporting and reflects overall management of Hirschsprung's disease within the UK↗
▶Ep 23 · 9:04
clinicalThe Tanzania study used trained carers to direct the method of cleansing, concentrating on areas known to harbor commensal and pathogenic bacteria↗
▶Ep 23 · 11:04
opinionThe Tanzania soap bathing trial was well designed, analyzed in substantial detail, and has implications for low to middle income countries where surgical site infections are a major problem↗
Journal of Pediatric Surgery Article Review: Q1 (Jan-Mar) 2024
▶Ep 31 · 7:32
opinionThe Newcastle series is a pushback series which extols relatively conventional open surgery and begs the question as to what role lengthening procedures have in those with long gaps.↗
▶Ep 31 · 7:32
quoteNevertheless, this is definitely a pushback series which extols relatively conventional open surgery, of course. It really, it really does beg the question as to what role and they would say, if any, er lengthening procedures have in those with er with long gaps.↗
Mark's statements about Esophageal Atresia17 statements
Journal of Pediatric Surgery Article Review: February 2023, BAPS issue
▶Ep 35 · 3:38
clinicalThe Centre in Rocklaw has become the referral center for esophageal atresia and long gap esophageal atresia cases from the whole of Poland↗
▶Ep 35 · 6:35
opinionThe Sheffield study represents real life surgical reporting and reflects overall management of Hirschsprung's disease within the UK↗
▶Ep 35 · 9:04
clinicalThe Tanzania study used trained carers to direct the method of cleansing, concentrating on areas known to harbor commensal and pathogenic bacteria↗
▶Ep 35 · 11:04
opinionThe Tanzania soap bathing trial was well designed, analyzed in substantial detail, and has implications for low to middle income countries where surgical site infections are a major problem↗
Journal of Pediatric Surgery Article Review: Q1 (Jan-Mar) 2024
▶Ep 59 · 7:32
quoteNevertheless, this is definitely a pushback series which extols relatively conventional open surgery, of course. It really, it really does beg the question as to what role and they would say, if any, er lengthening procedures have in those with er with long gaps.↗
▶Ep 59 · 7:32
opinionThe Newcastle series is a pushback series which extols relatively conventional open surgery and begs the question as to what role lengthening procedures have in those with long gaps.↗
Journal of Pediatric Surgery Article Review: February 2022 - BAPS Issue
▶Ep 74 · 1:11
quoteMy main interest was always to try and work out why. Babies are sometimes born without kidneys or without normal kidneys or without normal lower urinary tract↗
▶Ep 74 · 1:11
clinicalAdrian Wolf's research focuses on creating renal organoids with glomerular differentiation from pluripotent stem cells to understand why babies are born without kidneys or with abnormal kidneys or lower urinary tract.↗
▶Ep 74 · 2:05
opinionRenal organoids could potentially be used as replacement therapy instead of formal kidney transplant and could one day be functionally useful in living patients.↗
▶Ep 74 · 2:12
quoteOne day these could be functionally useful in actually a living patient.↗
▶Ep 74 · 2:23
clinicalStem cells can be made from blood samples of children born with abnormal kidneys to grow organoids in culture that reproduce the disease in a dish, allowing researchers to look for druggable targets.↗
▶Ep 74 · 2:44
clinicalGrowing a ureter from stem cells is difficult, and without a ureter, even a functional kidney organoid would have nowhere for urine to go.↗
▶Ep 74 · 2:50
quoteWithout the ureter, of course, you know, you can have a little kidney and even if it could make urine, the urine would have nowhere to go.↗
▶Ep 74 · 3:21
clinicalKidney organoids cannot be connected to large arteries, and their glomeruli could not make much urine without high pressure, high flow blood supply.↗
▶Ep 74 · 3:21
quoteWe cannot connect these little kidney organoids to a big artery.↗
▶Ep 74 · 5:19
quoteIt seems to reflect what is happening in the real world and clearly it's not universally successful, and its role in the management of long gap esophageal atresia, I think, will still remain controversial.↗
▶Ep 74 · 5:19
opinionMark Davenport states that ELBT results reflect what is happening in the real world, it is not universally successful, and its role in long gap esophageal atresia management will remain controversial.↗
Mark's statements about Hirschsprung disease4 statements
Journal of Pediatric Surgery Article Review: February 2023, BAPS issue
▶Ep 55 · 3:38
clinicalThe Centre in Rocklaw has become the referral center for esophageal atresia and long gap esophageal atresia cases from the whole of Poland↗
▶Ep 55 · 6:35
opinionThe Sheffield study represents real life surgical reporting and reflects overall management of Hirschsprung's disease within the UK↗
▶Ep 55 · 9:04
clinicalThe Tanzania study used trained carers to direct the method of cleansing, concentrating on areas known to harbor commensal and pathogenic bacteria↗
▶Ep 55 · 11:04
opinionThe Tanzania soap bathing trial was well designed, analyzed in substantial detail, and has implications for low to middle income countries where surgical site infections are a major problem↗
Mark's statements about Intussusception14 statements
Journal of Pediatric Surgery Article Review: The Disruption Score
▶Ep 8 · 2:34
clinicalThe H-index (Hirsch index) represents the influence or impact of a particular author, with higher values indicating greater impact.↗
▶Ep 8 · 2:58
epidemiologicalDr. George Holcomb has an H-index of 51, reflecting extensive publication over his surgical career.↗
▶Ep 8 · 3:07
epidemiologicalDr. Shah, the senior author of the disruption score paper, has an H-index of 8, which is typical of a fairly average pediatric surgeon.↗
▶Ep 8 · 3:43
clinicalIf future papers cite only the index paper and not its references, that paper is considered more disruptive; if they cite both the index paper and its references, it is less disruptive and more developmental.↗
▶Ep 8 · 7:18
quoteWell, I wouldn't have a real problem with this one, this is, uh, Michael Gower's paper, um, describing percutaneous endoscopic gastrostomies.↗
▶Ep 8 · 7:18
epidemiologicalMichael Gauderer's paper describing percutaneous endoscopic gastrostomies, with Jeff Ponsky as second author, ranked number 1 in the top 100 most disruptive papers.↗
▶Ep 8 · 7:26
quoteYou'll see the second author there is quite familiar, it's got a quite familiar name, that's Todd's dad.↗
▶Ep 8 · 7:51
epidemiologicalThe number 2 ranked paper was a large series on intussusception.↗
▶Ep 8 · 7:54
epidemiologicalThe number 3 ranked paper was a large series on fundoplications.↗
▶Ep 8 · 8:02
quoteBut some of them you think, why are they on this list?↗
▶Ep 8 · 8:05
epidemiologicalA paper on internet use in families of children requiring cardiac surgery ranked number 6, which Dr. Davenport found surprising.↗
▶Ep 8 · 8:12
epidemiologicalA case report on fibrous fusion between liver and lung, cited only 17 times, ranked number 7 on the list.↗
▶Ep 8 · 10:20
opinionDr. Davenport considers the article original but does not believe the disruption score stands up by comparison to conventional citation scores as the key method of assessing a paper's impact.↗
▶Ep 8 · 10:29
quoteI don't really think it stands up by comparison to the more conventional aspects of how we view the medical literature, the citation scores seems to be still uh the key method of assessing the impact of a particular uh paper.↗
Mark's statements about Long-gap Esophageal Atresia4 statements
Journal of Pediatric Surgery Article Review: February 2023, BAPS issue
▶Ep 4 · 3:38
clinicalThe Centre in Rocklaw has become the referral center for esophageal atresia and long gap esophageal atresia cases from the whole of Poland↗
▶Ep 4 · 6:35
opinionThe Sheffield study represents real life surgical reporting and reflects overall management of Hirschsprung's disease within the UK↗
▶Ep 4 · 9:04
clinicalThe Tanzania study used trained carers to direct the method of cleansing, concentrating on areas known to harbor commensal and pathogenic bacteria↗
▶Ep 4 · 11:04
opinionThe Tanzania soap bathing trial was well designed, analyzed in substantial detail, and has implications for low to middle income countries where surgical site infections are a major problem↗
Mark's statements about Long Gap Esophageal Atresia15 statements
Journal of Pediatric Surgery Article Review: February 2023, BAPS issue
▶Ep 5 · 3:38
clinicalThe Centre in Rocklaw has become the referral center for esophageal atresia and long gap esophageal atresia cases from the whole of Poland↗
▶Ep 5 · 6:35
opinionThe Sheffield study represents real life surgical reporting and reflects overall management of Hirschsprung's disease within the UK↗
▶Ep 5 · 9:04
clinicalThe Tanzania study used trained carers to direct the method of cleansing, concentrating on areas known to harbor commensal and pathogenic bacteria↗
▶Ep 5 · 11:04
opinionThe Tanzania soap bathing trial was well designed, analyzed in substantial detail, and has implications for low to middle income countries where surgical site infections are a major problem↗
Journal of Pediatric Surgery Article Review: February 2022 - BAPS Issue
▶Ep 8 · 1:11
clinicalAdrian Wolf's research focuses on creating renal organoids with glomerular differentiation from pluripotent stem cells to understand why babies are born without kidneys or with abnormal kidneys or lower urinary tract.↗
▶Ep 8 · 1:11
quoteMy main interest was always to try and work out why. Babies are sometimes born without kidneys or without normal kidneys or without normal lower urinary tract↗
▶Ep 8 · 2:05
opinionRenal organoids could potentially be used as replacement therapy instead of formal kidney transplant and could one day be functionally useful in living patients.↗
▶Ep 8 · 2:12
quoteOne day these could be functionally useful in actually a living patient.↗
▶Ep 8 · 2:23
clinicalStem cells can be made from blood samples of children born with abnormal kidneys to grow organoids in culture that reproduce the disease in a dish, allowing researchers to look for druggable targets.↗
▶Ep 8 · 2:44
clinicalGrowing a ureter from stem cells is difficult, and without a ureter, even a functional kidney organoid would have nowhere for urine to go.↗
▶Ep 8 · 2:50
quoteWithout the ureter, of course, you know, you can have a little kidney and even if it could make urine, the urine would have nowhere to go.↗
▶Ep 8 · 3:21
clinicalKidney organoids cannot be connected to large arteries, and their glomeruli could not make much urine without high pressure, high flow blood supply.↗
▶Ep 8 · 3:21
quoteWe cannot connect these little kidney organoids to a big artery.↗
▶Ep 8 · 5:19
quoteIt seems to reflect what is happening in the real world and clearly it's not universally successful, and its role in the management of long gap esophageal atresia, I think, will still remain controversial.↗
▶Ep 8 · 5:19
opinionMark Davenport states that ELBT results reflect what is happening in the real world, it is not universally successful, and its role in long gap esophageal atresia management will remain controversial.↗
Mark's statements about Pectus Excavatum6 statements
Journal of Pediatric Surgery Article Review: Q1 (Jan-Mar) 2024
▶Ep 44 · 4:44
quoteSo this is a 25 year experience. Description of 220 consecutive infants with esophageresia in Newcastle.↗
▶Ep 44 · 4:44
clinicalThe esophageal atresia study is a 25 year experience describing 220 consecutive infants with esophageal atresia in Newcastle.↗
▶Ep 44 · 7:32
opinionThe Newcastle series is a pushback series which extols relatively conventional open surgery and begs the question as to what role lengthening procedures have in those with long gaps.↗
▶Ep 44 · 7:32
quoteNevertheless, this is definitely a pushback series which extols relatively conventional open surgery, of course. It really, it really does beg the question as to what role and they would say, if any, er lengthening procedures have in those with er with long gaps.↗
▶Ep 44 · 7:32
quoteNevertheless, this is definitely a pushback series which extols relatively conventional open surgery, of course. It really, it really does beg the question as to what role and they would say, if any, er lengthening procedures have in those with er with long gaps.↗
▶Ep 44 · 7:32
opinionThe Newcastle series is a pushback series which extols relatively conventional open surgery and begs the question as to what role lengthening procedures have in those with long gaps.↗
Summaries Mark gave as host
· 18 summaries
Recaps of other experts' statements, not Mark's own clinical position.
Summaries Mark gave as host · Colorectal / ARM & Hirschsprung1 summary
Journal of Pediatric Surgery Article Review: February 2023, BAPS issue
▶Ep 135 · 9:53
host summaryMark Davenport summarizing the discussion: Length of stay in the soap bathing intervention group was 12 days compared to 22 days in the non-intervention group↗
Summaries Mark gave as host · Complicated Appendicitis2 summaries
Journal of Pediatric Surgery Article Review: Q1 (Jan-Mar) 2024
▶Ep 4 · 4:44
host summaryMark Davenport summarizing the discussion: The esophageal atresia study is a 25 year experience describing 220 consecutive infants with esophageal atresia in Newcastle.↗
▶Ep 4 · 4:44
host summaryMark Davenport summarizing the discussion: So this is a 25 year experience. Description of 220 consecutive infants with esophageresia in Newcastle.↗
Summaries Mark gave as host · Esophageal Atresia4 summaries
Journal of Pediatric Surgery Article Review: February 2023, BAPS issue
▶Ep 35 · 9:53
host summaryMark Davenport summarizing the discussion: Length of stay in the soap bathing intervention group was 12 days compared to 22 days in the non-intervention group↗
Journal of Pediatric Surgery Article Review: Q1 (Jan-Mar) 2024
▶Ep 59 · 4:44
host summaryMark Davenport summarizing the discussion: So this is a 25 year experience. Description of 220 consecutive infants with esophageresia in Newcastle.↗
▶Ep 59 · 4:44
host summaryMark Davenport summarizing the discussion: The esophageal atresia study is a 25 year experience describing 220 consecutive infants with esophageal atresia in Newcastle.↗
Journal of Pediatric Surgery Article Review: February 2022 - BAPS Issue
▶Ep 74 · 7:57
host summaryMark Davenport summarizing the discussion: In the United States, reimbursement is based on volume, which creates resistance to centralization as centers would give up a major part of their practice.↗
Summaries Mark gave as host · Esophageal Atresia3 summaries
Journal of Pediatric Surgery Article Review: February 2023, BAPS issue
▶Ep 23 · 9:53
host summaryMark Davenport summarizing the discussion: Length of stay in the soap bathing intervention group was 12 days compared to 22 days in the non-intervention group↗
Journal of Pediatric Surgery Article Review: Q1 (Jan-Mar) 2024
▶Ep 31 · 4:44
host summaryMark Davenport summarizing the discussion: So this is a 25 year experience. Description of 220 consecutive infants with esophageresia in Newcastle.↗
▶Ep 31 · 4:44
host summaryMark Davenport summarizing the discussion: The esophageal atresia study is a 25 year experience describing 220 consecutive infants with esophageal atresia in Newcastle.↗
Summaries Mark gave as host · Hirschsprung disease1 summary
Journal of Pediatric Surgery Article Review: February 2023, BAPS issue
▶Ep 55 · 9:53
host summaryMark Davenport summarizing the discussion: Length of stay in the soap bathing intervention group was 12 days compared to 22 days in the non-intervention group↗
Summaries Mark gave as host · Intussusception2 summaries
Journal of Pediatric Surgery Article Review: The Disruption Score
▶Ep 8 · 1:59
host summaryMark Davenport summarizing the discussion: They're going to calculate a so-called disruption score, this is a bibliometric tool, and they're going to use it to characterize essentially pediatric surgery publications.↗
▶Ep 8 · 1:59
host summaryMark Davenport summarizing the discussion: The disruption score is a bibliometric tool used to characterize pediatric surgery publications.↗
Summaries Mark gave as host · Long-gap Esophageal Atresia1 summary
Journal of Pediatric Surgery Article Review: February 2023, BAPS issue
▶Ep 4 · 9:53
host summaryMark Davenport summarizing the discussion: Length of stay in the soap bathing intervention group was 12 days compared to 22 days in the non-intervention group↗
Summaries Mark gave as host · Long Gap Esophageal Atresia2 summaries
Journal of Pediatric Surgery Article Review: February 2023, BAPS issue
▶Ep 5 · 9:53
host summaryMark Davenport summarizing the discussion: Length of stay in the soap bathing intervention group was 12 days compared to 22 days in the non-intervention group↗
Journal of Pediatric Surgery Article Review: February 2022 - BAPS Issue
▶Ep 8 · 7:57
host summaryMark Davenport summarizing the discussion: In the United States, reimbursement is based on volume, which creates resistance to centralization as centers would give up a major part of their practice.↗
Summaries Mark gave as host · Pectus Excavatum2 summaries
Journal of Pediatric Surgery Article Review: Q1 (Jan-Mar) 2024
▶Ep 44 · 4:44
host summaryMark Davenport summarizing the discussion: So this is a 25 year experience. Description of 220 consecutive infants with esophageresia in Newcastle.↗
▶Ep 44 · 4:44
host summaryMark Davenport summarizing the discussion: The esophageal atresia study is a 25 year experience describing 220 consecutive infants with esophageal atresia in Newcastle.↗
