142 statements
· 4 topics
· summaries given as host listed separately
Featured statements
▶Ep 21 · 1:22
There's a lot of controversy about the timing of all of this, but really what it boils down to is if you have a child who's got ongoing respiratory symptoms, they're having aspiration, they're failing to thrive, they're having recurrent pulmonary infections, and they've failed all the other stuff, or in some instances before you even try all the other stuff, you operate on them.
It doesn't matter if you do this in a mass closure technique or a layered closure technique, but the key is when you're done, you have to make sure that your edges are inverted.
I always prefer to go with cold steel, especially on the minor ones, because it's more simple to set up, and you can't have a laser fire if you don't use the laser.
Lipid-laden macrophages are a limited tool because aspirated material has variable lipid content (saliva has no lipid), there is variable time between aspiration and BAL sampling affecting lipid metabolism, and individuals have variable rates of lipid catabolism.
Aerodigestive Management of Pediatric Aspiration - FULL SHOW
▶Ep 7 · 0:16
clinicalAspiration is defined as any solid or liquid matter passing below the vocal cords, though some define it as requiring pulmonary compromise in addition to passage below the cords.↗
▶Ep 7 · 0:39
clinicalAspiration can be silent with no clinical indication, or obvious with coughing, choking, and sputtering.↗
▶Ep 7 · 1:51
epidemiologicalChildren with CHARGE syndrome have 80 to 90% prevalence of aspiration at some point in their lifetime and should be assumed to aspirate until proven otherwise.↗
▶Ep 7 · 2:01
clinicalChildren with severe neurologic compromise regardless of etiology should be assumed to aspirate until demonstrated otherwise.↗
▶Ep 7 · 2:32
clinicalThe clinical significance of aspiration depends on the quantity—small isolated events are usually cleared by host defenses (cough, mucociliary transport), while large or repeated events overcome host defenses.↗
▶Ep 7 · 3:06
clinicalA single aspiration event of caustic substance can have lifelong consequences.↗
▶Ep 7 · 3:31
clinicalChronic pulmonary aspiration is defined as repeated aspiration into the lower airways causing pulmonary injury or chronic respiratory disease, with consequences determined by frequency, magnitude, nature of material, and effectiveness of host defenses.↗
▶Ep 7 · 3:31
clinicalChronic pulmonary aspiration is defined as repeated aspiration into the lower airways causing pulmonary injury or chronic respiratory disease, with consequences determined by frequency, magnitude, nature of material, and effectiveness of host defenses.↗
▶Ep 7 · 4:34
clinicalFour major groups aspirate: premature babies, those with neurologic disabilities, those with airway disease (anatomic, dynamic, or functional), and those with gastrointestinal disorders.↗
▶Ep 7 · 4:34
clinicalFour major groups aspirate: premature babies, those with neurologic disabilities, those with airway disease (anatomic, dynamic, or functional), and those with gastrointestinal disorders.↗
▶Ep 7 · 5:02
clinicalSyndromes with significant swallowing dysfunction include CHARGE, Cri-du-chat, Möbius syndrome (cranial nerve abnormalities), and craniofacial defects like Pfeiffer, Crouzon, and Treacher Collins.↗
▶Ep 7 · 44:25
clinicalLipid-laden macrophages are the most commonly used aspiration biomarker, with a lipid-laden macrophage index >90 or >20% of macrophages containing lipid suggesting aspiration.↗
▶Ep 7 · 45:56
clinicalElevated lipid-laden macrophages are not pathognomonic of aspiration—they can result from natural airway debris (dead neutrophils, macrophages from inflammation) or circulation after bleeding or airway surgery.↗
▶Ep 7 · 45:56
clinicalElevated lipid-laden macrophages are not pathognomonic of aspiration—they can result from natural airway debris (dead neutrophils, macrophages from inflammation) or circulation after bleeding or airway surgery.↗
▶Ep 7 · 46:38
clinicalLipid-laden macrophages are a limited tool because aspirated material has variable lipid content (saliva has no lipid), there is variable time between aspiration and BAL sampling affecting lipid metabolism, and individuals have variable rates of lipid catabolism.↗
▶Ep 7 · 46:38
clinicalLipid-laden macrophages are a limited tool because aspirated material has variable lipid content (saliva has no lipid), there is variable time between aspiration and BAL sampling affecting lipid metabolism, and individuals have variable rates of lipid catabolism.↗
▶Ep 7 · 48:08
clinicalHaving a tracheostomy tube changes the dynamics of laryngeal elevation but most studies show it does not create aspiration.↗
▶Ep 7 · 49:10
quoteIt's not what you get in, it's how you get it out.↗
▶Ep 7 · 49:10
clinicalDecanulation should not proceed until the child has proven capacity to clear their airway through a prolonged capping trial that includes going through illnesses without needing the tracheostomy for clearance.↗
▶Ep 7 · 49:10
quoteIt's not what you get in, it's how you get it out.↗
▶Ep 7 · 49:10
clinicalDecanulation should not proceed until the child has proven capacity to clear their airway through a prolonged capping trial that includes going through illnesses without needing the tracheostomy for clearance.↗
▶Ep 7 · 49:56
clinicalSpeaking valves help with airway clearance by allowing glottic closure for better cough and creating positive end-expiratory pressure that distends airways, even if they do not decrease aspiration coming in.↗
▶Ep 7 · 49:56
clinicalSpeaking valves help with airway clearance by allowing glottic closure for better cough and creating positive end-expiratory pressure that distends airways, even if they do not decrease aspiration coming in.↗
▶Ep 7 · 51:44
opinionThe pulmonologist's role in the aerodigestive team is to protect children from developing irreversible long-term pulmonary sequelae while managing anatomic abnormalities or waiting for maturity.↗
▶Ep 7 · 51:44
opinionThe pulmonologist's role in the aerodigestive team is to protect children from developing irreversible long-term pulmonary sequelae while managing anatomic abnormalities or waiting for maturity.↗
▶Ep 7 · 58:16
clinicalMedical management of functional aspiration should target five aspects: decrease aspiration events, improve airway clearance, address quality of aspirated material, control inflammation, and treat or prevent infections.↗
▶Ep 7 · 58:16
clinicalMedical management of functional aspiration should target five aspects: decrease aspiration events, improve airway clearance, address quality of aspirated material, control inflammation, and treat or prevent infections.↗
▶Ep 7 · 1:00:11
clinicalFor airway clearance, comorbidities that compromise clearance include tracheobronchomalacia, airway compression/stenosis/hypoplasia, restrictive lung disease (neuromuscular, chest wall deformities, scoliosis), and vocal cord or diaphragmatic dysfunction/paralysis from esophageal or cardiac surgery.↗
▶Ep 7 · 1:02:17
clinicalChronic inflammation from aspiration is managed with inhaled steroids and systemic anti-inflammatory medication (azithromycin, not systemic steroids as first-line), with systemic steroids reserved for acute aspiration events to prevent pneumonitis.↗
▶Ep 7 · 1:02:17
clinicalChronic inflammation from aspiration is managed with inhaled steroids and systemic anti-inflammatory medication (azithromycin, not systemic steroids as first-line), with systemic steroids reserved for acute aspiration events to prevent pneumonitis.↗
▶Ep 7 · 1:03:30
clinicalPatients with bronchiectasis from chronic aspiration should receive longer antibiotic courses (10-14 days instead of 7-10 days) because bronchiectatic cavities have more difficult clearance.↗
▶Ep 7 · 1:03:30
clinicalPatients with bronchiectasis from chronic aspiration should receive longer antibiotic courses (10-14 days instead of 7-10 days) because bronchiectatic cavities have more difficult clearance.↗
▶Ep 7 · 1:03:42
clinicalProphylactic inhaled antibiotics (tobramycin or colistimethate, either every other month or 14 days per month) are reserved for patients with severe bronchiectasis and pulmonary injury or significant frequency of infections.↗
▶Ep 7 · 1:03:42
clinicalProphylactic inhaled antibiotics (tobramycin or colistimethate, either every other month or 14 days per month) are reserved for patients with severe bronchiectasis and pulmonary injury or significant frequency of infections.↗
▶Ep 7 · 1:04:56
clinicalCuff tubes cannot stop aspiration because inflating the cuff enough to decrease leak causes unacceptable tracheal injury or dilation.↗
▶Ep 7 · 1:04:56
clinicalCuff tubes cannot stop aspiration because inflating the cuff enough to decrease leak causes unacceptable tracheal injury or dilation.↗
▶Ep 7 · 1:05:45
clinicalPositive pressure ventilation (CPAP or BiPAP) can decrease aspiration events, especially during sleep in patients with reflux aspiration, even in patients who do not need it for gas exchange or ventilation.↗
▶Ep 7 · 1:05:45
clinicalPositive pressure ventilation (CPAP or BiPAP) can decrease aspiration events, especially during sleep in patients with reflux aspiration, even in patients who do not need it for gas exchange or ventilation.↗
▶Ep 7 · 1:06:39
clinicalPassy-Muir valves should never be used during sleep because they allow inhalation through the tracheostomy but not exhalation, risking obstruction from mucus accumulation, and they cause over-drying of secretions leading to mucus plugging.↗
▶Ep 7 · 1:06:39
clinicalPassy-Muir valves should never be used during sleep because they allow inhalation through the tracheostomy but not exhalation, risking obstruction from mucus accumulation, and they cause over-drying of secretions leading to mucus plugging.↗
QUAD #20: Endoscopic Repair of Minor Laryngeal Clefts with Dr. Catherine Hart
▶Ep 21 · 0:48
quoteThis is a child. We had a really high index of suspicion had a cleft, and you can see there that that looks. Incredibly normal on that flexible bronchoscopy.↗
▶Ep 21 · 0:48
clinicalA type 1 laryngeal cleft can appear normal on flexible bronchoscopy but be visible on rigid bronchoscopy using less sophisticated identification techniques.↗
▶Ep 21 · 0:56
quoteAnd even here using the less sophisticated technique that we use to identify cleft in Cincinnati, you can see this kid's got a type 1 cleft.↗
▶Ep 21 · 1:09
clinicalCombined flexible and rigid bronchoscopy evaluations are complementary and necessary to avoid missing laryngeal clefts.↗
▶Ep 21 · 1:09
quoteSo I think this really speaks to the importance of these combined evaluations that we do, and those two evaluations are truly complementary, and you miss stuff if you don't do them both.↗
▶Ep 21 · 1:22
quoteThere's a lot of controversy about the timing of all of this, but really what it boils down to is if you have a child who's got ongoing respiratory symptoms, they're having aspiration, they're failing to thrive, they're having recurrent pulmonary infections, and they've failed all the other stuff, or in some instances before you even try all the other stuff, you operate on them.↗
▶Ep 21 · 1:22
clinicalSurgical indications for laryngeal cleft repair include ongoing respiratory symptoms, aspiration, failure to thrive, recurrent pulmonary infections, and failure of conservative measures (or in some instances before trying conservative measures).↗
▶Ep 21 · 1:52
quoteIt doesn't matter if you do this in a mass closure technique or a layered closure technique, but the key is when you're done, you have to make sure that your edges are inverted.↗
▶Ep 21 · 1:52
clinicalMass closure or layered closure technique can be used for laryngeal cleft repair, but the key requirement is that edges must be inverted when finished.↗
▶Ep 21 · 2:30
opinionCold steel is preferred over laser for minor cleft resection because it is simpler to set up, faster, and eliminates the risk of laser fire.↗
▶Ep 21 · 2:30
quoteI always prefer to go with cold steel, especially on the minor ones, because it's more simple to set up, and you can't have a laser fire if you don't use the laser.↗
▶Ep 21 · 2:39
quoteThat's why we typically do it this way, and it's just a heck of a lot faster.↗
▶Ep 21 · 2:52
clinicalClosure is performed using interrupted sutures, typically PDS on an RB1 or P3 needle depending on child size.↗
▶Ep 21 · 3:10
clinicalPostoperatively, children are observed overnight on the airway unit and resume their preoperative diet, which is continued until postoperative evaluation.↗
▶Ep 21 · 3:15
clinicalPostoperative evaluation is typically performed 6 to 8 weeks after surgery and includes repeat video swallow study and repeat endoscopy to ensure healing.↗
▶Ep 21 · 3:29
clinicalFailure of endoscopic cleft repair is not super common.↗
▶Ep 21 · 3:32
clinicalIncomplete demucosalization at the apex can result in healing at the top but a gap remaining at the back.↗
▶Ep 21 · 3:46
opinionLayered closure technique (closing anterior and posterior portions separately) seems like more effort in minor clefts but is a more reasonable option for type 2 or 3 clefts to ensure good closure.↗
▶Ep 21 · 4:09
epidemiologicalConservative management (not surgery) achieves resolution over time in 51% of children with laryngeal clefts.↗
▶Ep 21 · 4:09
quoteWhen you compare conservative management. Other different therapies in either injection or surgical closure, get resolution over time in 51% of kids.↗
▶Ep 21 · 4:19
quoteSo by doing not nothing, but not doing surgery, you can still get improvement in a lot of patients.↗
▶Ep 21 · 4:24
quoteWhen you look at injection laryngoplasty in this big group, they get improvement in symptoms in 2/3 of kids with resolution in 1/3.↗
▶Ep 21 · 4:24
epidemiologicalInjection laryngoplasty achieves improvement in symptoms in two-thirds of children and resolution in one-third.↗
▶Ep 21 · 4:45
clinicalComplications of surgical cleft repair are often not terrible but include reports of laryngeal scarring, supraglottic infections, and lacerations.↗
Katherine's statements about Aspiration39 statements
Aerodigestive Management of Pediatric Aspiration - FULL SHOW
▶Ep 1 · 3:31
clinicalChronic pulmonary aspiration is defined as repeated aspiration into the lower airways causing pulmonary injury or chronic respiratory disease, with consequences determined by frequency, magnitude, nature of material, and effectiveness of host defenses.↗
▶Ep 1 · 4:34
clinicalFour major groups aspirate: premature babies, those with neurologic disabilities, those with airway disease (anatomic, dynamic, or functional), and those with gastrointestinal disorders.↗
▶Ep 1 · 45:56
clinicalElevated lipid-laden macrophages are not pathognomonic of aspiration—they can result from natural airway debris (dead neutrophils, macrophages from inflammation) or circulation after bleeding or airway surgery.↗
▶Ep 1 · 46:38
clinicalLipid-laden macrophages are a limited tool because aspirated material has variable lipid content (saliva has no lipid), there is variable time between aspiration and BAL sampling affecting lipid metabolism, and individuals have variable rates of lipid catabolism.↗
▶Ep 1 · 49:10
quoteIt's not what you get in, it's how you get it out.↗
▶Ep 1 · 49:10
clinicalDecanulation should not proceed until the child has proven capacity to clear their airway through a prolonged capping trial that includes going through illnesses without needing the tracheostomy for clearance.↗
▶Ep 1 · 49:56
clinicalSpeaking valves help with airway clearance by allowing glottic closure for better cough and creating positive end-expiratory pressure that distends airways, even if they do not decrease aspiration coming in.↗
▶Ep 1 · 51:44
opinionThe pulmonologist's role in the aerodigestive team is to protect children from developing irreversible long-term pulmonary sequelae while managing anatomic abnormalities or waiting for maturity.↗
▶Ep 1 · 58:16
clinicalMedical management of functional aspiration should target five aspects: decrease aspiration events, improve airway clearance, address quality of aspirated material, control inflammation, and treat or prevent infections.↗
▶Ep 1 · 1:02:17
clinicalChronic inflammation from aspiration is managed with inhaled steroids and systemic anti-inflammatory medication (azithromycin, not systemic steroids as first-line), with systemic steroids reserved for acute aspiration events to prevent pneumonitis.↗
▶Ep 1 · 1:03:30
clinicalPatients with bronchiectasis from chronic aspiration should receive longer antibiotic courses (10-14 days instead of 7-10 days) because bronchiectatic cavities have more difficult clearance.↗
▶Ep 1 · 1:03:42
clinicalProphylactic inhaled antibiotics (tobramycin or colistimethate, either every other month or 14 days per month) are reserved for patients with severe bronchiectasis and pulmonary injury or significant frequency of infections.↗
▶Ep 1 · 1:04:56
clinicalCuff tubes cannot stop aspiration because inflating the cuff enough to decrease leak causes unacceptable tracheal injury or dilation.↗
▶Ep 1 · 1:05:45
clinicalPositive pressure ventilation (CPAP or BiPAP) can decrease aspiration events, especially during sleep in patients with reflux aspiration, even in patients who do not need it for gas exchange or ventilation.↗
▶Ep 1 · 1:06:39
clinicalPassy-Muir valves should never be used during sleep because they allow inhalation through the tracheostomy but not exhalation, risking obstruction from mucus accumulation, and they cause over-drying of secretions leading to mucus plugging.↗
QUAD #20: Endoscopic Repair of Minor Laryngeal Clefts with Dr. Catherine Hart
▶Ep 5 · 0:48
quoteThis is a child. We had a really high index of suspicion had a cleft, and you can see there that that looks. Incredibly normal on that flexible bronchoscopy.↗
▶Ep 5 · 0:48
clinicalA type 1 laryngeal cleft can appear normal on flexible bronchoscopy but be visible on rigid bronchoscopy using less sophisticated identification techniques.↗
▶Ep 5 · 0:56
quoteAnd even here using the less sophisticated technique that we use to identify cleft in Cincinnati, you can see this kid's got a type 1 cleft.↗
▶Ep 5 · 1:09
quoteSo I think this really speaks to the importance of these combined evaluations that we do, and those two evaluations are truly complementary, and you miss stuff if you don't do them both.↗
▶Ep 5 · 1:09
clinicalCombined flexible and rigid bronchoscopy evaluations are complementary and necessary to avoid missing laryngeal clefts.↗
▶Ep 5 · 1:22
clinicalSurgical indications for laryngeal cleft repair include ongoing respiratory symptoms, aspiration, failure to thrive, recurrent pulmonary infections, and failure of conservative measures (or in some instances before trying conservative measures).↗
▶Ep 5 · 1:22
quoteThere's a lot of controversy about the timing of all of this, but really what it boils down to is if you have a child who's got ongoing respiratory symptoms, they're having aspiration, they're failing to thrive, they're having recurrent pulmonary infections, and they've failed all the other stuff, or in some instances before you even try all the other stuff, you operate on them.↗
▶Ep 5 · 1:52
clinicalMass closure or layered closure technique can be used for laryngeal cleft repair, but the key requirement is that edges must be inverted when finished.↗
▶Ep 5 · 1:52
quoteIt doesn't matter if you do this in a mass closure technique or a layered closure technique, but the key is when you're done, you have to make sure that your edges are inverted.↗
▶Ep 5 · 2:30
opinionCold steel is preferred over laser for minor cleft resection because it is simpler to set up, faster, and eliminates the risk of laser fire.↗
▶Ep 5 · 2:30
quoteI always prefer to go with cold steel, especially on the minor ones, because it's more simple to set up, and you can't have a laser fire if you don't use the laser.↗
▶Ep 5 · 2:39
quoteThat's why we typically do it this way, and it's just a heck of a lot faster.↗
▶Ep 5 · 2:52
clinicalClosure is performed using interrupted sutures, typically PDS on an RB1 or P3 needle depending on child size.↗
▶Ep 5 · 3:10
clinicalPostoperatively, children are observed overnight on the airway unit and resume their preoperative diet, which is continued until postoperative evaluation.↗
▶Ep 5 · 3:15
clinicalPostoperative evaluation is typically performed 6 to 8 weeks after surgery and includes repeat video swallow study and repeat endoscopy to ensure healing.↗
▶Ep 5 · 3:29
clinicalFailure of endoscopic cleft repair is not super common.↗
▶Ep 5 · 3:32
clinicalIncomplete demucosalization at the apex can result in healing at the top but a gap remaining at the back.↗
▶Ep 5 · 3:46
opinionLayered closure technique (closing anterior and posterior portions separately) seems like more effort in minor clefts but is a more reasonable option for type 2 or 3 clefts to ensure good closure.↗
▶Ep 5 · 4:09
epidemiologicalConservative management (not surgery) achieves resolution over time in 51% of children with laryngeal clefts.↗
▶Ep 5 · 4:09
quoteWhen you compare conservative management. Other different therapies in either injection or surgical closure, get resolution over time in 51% of kids.↗
▶Ep 5 · 4:19
quoteSo by doing not nothing, but not doing surgery, you can still get improvement in a lot of patients.↗
▶Ep 5 · 4:24
epidemiologicalInjection laryngoplasty achieves improvement in symptoms in two-thirds of children and resolution in one-third.↗
▶Ep 5 · 4:24
quoteWhen you look at injection laryngoplasty in this big group, they get improvement in symptoms in 2/3 of kids with resolution in 1/3.↗
▶Ep 5 · 4:45
clinicalComplications of surgical cleft repair are often not terrible but include reports of laryngeal scarring, supraglottic infections, and lacerations.↗
Katherine's statements about CHARGE Syndrome15 statements
Aerodigestive Management of Pediatric Aspiration - FULL SHOW
▶Ep 2 · 3:31
clinicalChronic pulmonary aspiration is defined as repeated aspiration into the lower airways causing pulmonary injury or chronic respiratory disease, with consequences determined by frequency, magnitude, nature of material, and effectiveness of host defenses.↗
▶Ep 2 · 4:34
clinicalFour major groups aspirate: premature babies, those with neurologic disabilities, those with airway disease (anatomic, dynamic, or functional), and those with gastrointestinal disorders.↗
▶Ep 2 · 45:56
clinicalElevated lipid-laden macrophages are not pathognomonic of aspiration—they can result from natural airway debris (dead neutrophils, macrophages from inflammation) or circulation after bleeding or airway surgery.↗
▶Ep 2 · 46:38
clinicalLipid-laden macrophages are a limited tool because aspirated material has variable lipid content (saliva has no lipid), there is variable time between aspiration and BAL sampling affecting lipid metabolism, and individuals have variable rates of lipid catabolism.↗
▶Ep 2 · 49:10
clinicalDecanulation should not proceed until the child has proven capacity to clear their airway through a prolonged capping trial that includes going through illnesses without needing the tracheostomy for clearance.↗
▶Ep 2 · 49:10
quoteIt's not what you get in, it's how you get it out.↗
▶Ep 2 · 49:56
clinicalSpeaking valves help with airway clearance by allowing glottic closure for better cough and creating positive end-expiratory pressure that distends airways, even if they do not decrease aspiration coming in.↗
▶Ep 2 · 51:44
opinionThe pulmonologist's role in the aerodigestive team is to protect children from developing irreversible long-term pulmonary sequelae while managing anatomic abnormalities or waiting for maturity.↗
▶Ep 2 · 58:16
clinicalMedical management of functional aspiration should target five aspects: decrease aspiration events, improve airway clearance, address quality of aspirated material, control inflammation, and treat or prevent infections.↗
▶Ep 2 · 1:02:17
clinicalChronic inflammation from aspiration is managed with inhaled steroids and systemic anti-inflammatory medication (azithromycin, not systemic steroids as first-line), with systemic steroids reserved for acute aspiration events to prevent pneumonitis.↗
▶Ep 2 · 1:03:30
clinicalPatients with bronchiectasis from chronic aspiration should receive longer antibiotic courses (10-14 days instead of 7-10 days) because bronchiectatic cavities have more difficult clearance.↗
▶Ep 2 · 1:03:42
clinicalProphylactic inhaled antibiotics (tobramycin or colistimethate, either every other month or 14 days per month) are reserved for patients with severe bronchiectasis and pulmonary injury or significant frequency of infections.↗
▶Ep 2 · 1:04:56
clinicalCuff tubes cannot stop aspiration because inflating the cuff enough to decrease leak causes unacceptable tracheal injury or dilation.↗
▶Ep 2 · 1:05:45
clinicalPositive pressure ventilation (CPAP or BiPAP) can decrease aspiration events, especially during sleep in patients with reflux aspiration, even in patients who do not need it for gas exchange or ventilation.↗
▶Ep 2 · 1:06:39
clinicalPassy-Muir valves should never be used during sleep because they allow inhalation through the tracheostomy but not exhalation, risking obstruction from mucus accumulation, and they cause over-drying of secretions leading to mucus plugging.↗
Katherine's statements about Laryngeal Cleft24 statements
QUAD #20: Endoscopic Repair of Minor Laryngeal Clefts with Dr. Catherine Hart
▶Ep 2 · 0:48
quoteThis is a child. We had a really high index of suspicion had a cleft, and you can see there that that looks. Incredibly normal on that flexible bronchoscopy.↗
▶Ep 2 · 0:48
clinicalA type 1 laryngeal cleft can appear normal on flexible bronchoscopy but be visible on rigid bronchoscopy using less sophisticated identification techniques.↗
▶Ep 2 · 0:56
quoteAnd even here using the less sophisticated technique that we use to identify cleft in Cincinnati, you can see this kid's got a type 1 cleft.↗
▶Ep 2 · 1:09
quoteSo I think this really speaks to the importance of these combined evaluations that we do, and those two evaluations are truly complementary, and you miss stuff if you don't do them both.↗
▶Ep 2 · 1:09
clinicalCombined flexible and rigid bronchoscopy evaluations are complementary and necessary to avoid missing laryngeal clefts.↗
▶Ep 2 · 1:22
quoteThere's a lot of controversy about the timing of all of this, but really what it boils down to is if you have a child who's got ongoing respiratory symptoms, they're having aspiration, they're failing to thrive, they're having recurrent pulmonary infections, and they've failed all the other stuff, or in some instances before you even try all the other stuff, you operate on them.↗
▶Ep 2 · 1:22
clinicalSurgical indications for laryngeal cleft repair include ongoing respiratory symptoms, aspiration, failure to thrive, recurrent pulmonary infections, and failure of conservative measures (or in some instances before trying conservative measures).↗
▶Ep 2 · 1:52
clinicalMass closure or layered closure technique can be used for laryngeal cleft repair, but the key requirement is that edges must be inverted when finished.↗
▶Ep 2 · 1:52
quoteIt doesn't matter if you do this in a mass closure technique or a layered closure technique, but the key is when you're done, you have to make sure that your edges are inverted.↗
▶Ep 2 · 2:30
opinionCold steel is preferred over laser for minor cleft resection because it is simpler to set up, faster, and eliminates the risk of laser fire.↗
▶Ep 2 · 2:30
quoteI always prefer to go with cold steel, especially on the minor ones, because it's more simple to set up, and you can't have a laser fire if you don't use the laser.↗
▶Ep 2 · 2:39
quoteThat's why we typically do it this way, and it's just a heck of a lot faster.↗
▶Ep 2 · 2:52
clinicalClosure is performed using interrupted sutures, typically PDS on an RB1 or P3 needle depending on child size.↗
▶Ep 2 · 3:10
clinicalPostoperatively, children are observed overnight on the airway unit and resume their preoperative diet, which is continued until postoperative evaluation.↗
▶Ep 2 · 3:15
clinicalPostoperative evaluation is typically performed 6 to 8 weeks after surgery and includes repeat video swallow study and repeat endoscopy to ensure healing.↗
▶Ep 2 · 3:29
clinicalFailure of endoscopic cleft repair is not super common.↗
▶Ep 2 · 3:32
clinicalIncomplete demucosalization at the apex can result in healing at the top but a gap remaining at the back.↗
▶Ep 2 · 3:46
opinionLayered closure technique (closing anterior and posterior portions separately) seems like more effort in minor clefts but is a more reasonable option for type 2 or 3 clefts to ensure good closure.↗
▶Ep 2 · 4:09
epidemiologicalConservative management (not surgery) achieves resolution over time in 51% of children with laryngeal clefts.↗
▶Ep 2 · 4:09
quoteWhen you compare conservative management. Other different therapies in either injection or surgical closure, get resolution over time in 51% of kids.↗
▶Ep 2 · 4:19
quoteSo by doing not nothing, but not doing surgery, you can still get improvement in a lot of patients.↗
▶Ep 2 · 4:24
epidemiologicalInjection laryngoplasty achieves improvement in symptoms in two-thirds of children and resolution in one-third.↗
▶Ep 2 · 4:24
quoteWhen you look at injection laryngoplasty in this big group, they get improvement in symptoms in 2/3 of kids with resolution in 1/3.↗
▶Ep 2 · 4:45
clinicalComplications of surgical cleft repair are often not terrible but include reports of laryngeal scarring, supraglottic infections, and lacerations.↗
Summaries Katherine gave as host
· 30 summaries
Recaps of other experts' statements, not Katherine's own clinical position.
Summaries Katherine gave as host · Aerodigestive / ENT10 summaries
Aerodigestive Management of Pediatric Aspiration - FULL SHOW
▶Ep 7 · 0:16
host summaryKatherine Hart summarizing the discussion: Aspiration is defined as any solid or liquid matter passing below the vocal cords, though some define it as requiring pulmonary compromise in addition to passage below the cords.↗
▶Ep 7 · 0:39
host summaryKatherine Hart summarizing the discussion: Aspiration can be silent with no clinical indication, or obvious with coughing, choking, and sputtering.↗
▶Ep 7 · 1:51
host summaryKatherine Hart summarizing the discussion: Children with CHARGE syndrome have 80 to 90% prevalence of aspiration at some point in their lifetime and should be assumed to aspirate until proven otherwise.↗
▶Ep 7 · 2:01
host summaryKatherine Hart summarizing the discussion: Children with severe neurologic compromise regardless of etiology should be assumed to aspirate until demonstrated otherwise.↗
▶Ep 7 · 2:32
host summaryKatherine Hart summarizing the discussion: The clinical significance of aspiration depends on the quantity—small isolated events are usually cleared by host defenses (cough, mucociliary transport), while large or repeated events overcome host defenses.↗
▶Ep 7 · 3:06
host summaryKatherine Hart summarizing the discussion: A single aspiration event of caustic substance can have lifelong consequences.↗
▶Ep 7 · 5:02
host summaryKatherine Hart summarizing the discussion: Syndromes with significant swallowing dysfunction include CHARGE, Cri-du-chat, Möbius syndrome (cranial nerve abnormalities), and craniofacial defects like Pfeiffer, Crouzon, and Treacher Collins.↗
▶Ep 7 · 44:25
host summaryKatherine Hart summarizing the discussion: Lipid-laden macrophages are the most commonly used aspiration biomarker, with a lipid-laden macrophage index >90 or >20% of macrophages containing lipid suggesting aspiration.↗
▶Ep 7 · 48:08
host summaryKatherine Hart summarizing the discussion: Having a tracheostomy tube changes the dynamics of laryngeal elevation but most studies show it does not create aspiration.↗
▶Ep 7 · 1:00:11
host summaryKatherine Hart summarizing the discussion: For airway clearance, comorbidities that compromise clearance include tracheobronchomalacia, airway compression/stenosis/hypoplasia, restrictive lung disease (neuromuscular, chest wall deformities, scoliosis), and vocal cord or diaphragmatic dysfunction/paralysis from esophageal or cardiac surgery.↗
Summaries Katherine gave as host · Aspiration10 summaries
Aerodigestive Management of Pediatric Aspiration - FULL SHOW
▶Ep 1 · 0:16
host summaryKatherine Hart summarizing the discussion: Aspiration is defined as any solid or liquid matter passing below the vocal cords, though some define it as requiring pulmonary compromise in addition to passage below the cords.↗
▶Ep 1 · 0:39
host summaryKatherine Hart summarizing the discussion: Aspiration can be silent with no clinical indication, or obvious with coughing, choking, and sputtering.↗
▶Ep 1 · 1:51
host summaryKatherine Hart summarizing the discussion: Children with CHARGE syndrome have 80 to 90% prevalence of aspiration at some point in their lifetime and should be assumed to aspirate until proven otherwise.↗
▶Ep 1 · 2:01
host summaryKatherine Hart summarizing the discussion: Children with severe neurologic compromise regardless of etiology should be assumed to aspirate until demonstrated otherwise.↗
▶Ep 1 · 2:32
host summaryKatherine Hart summarizing the discussion: The clinical significance of aspiration depends on the quantity—small isolated events are usually cleared by host defenses (cough, mucociliary transport), while large or repeated events overcome host defenses.↗
▶Ep 1 · 3:06
host summaryKatherine Hart summarizing the discussion: A single aspiration event of caustic substance can have lifelong consequences.↗
▶Ep 1 · 5:02
host summaryKatherine Hart summarizing the discussion: Syndromes with significant swallowing dysfunction include CHARGE, Cri-du-chat, Möbius syndrome (cranial nerve abnormalities), and craniofacial defects like Pfeiffer, Crouzon, and Treacher Collins.↗
▶Ep 1 · 44:25
host summaryKatherine Hart summarizing the discussion: Lipid-laden macrophages are the most commonly used aspiration biomarker, with a lipid-laden macrophage index >90 or >20% of macrophages containing lipid suggesting aspiration.↗
▶Ep 1 · 48:08
host summaryKatherine Hart summarizing the discussion: Having a tracheostomy tube changes the dynamics of laryngeal elevation but most studies show it does not create aspiration.↗
▶Ep 1 · 1:00:11
host summaryKatherine Hart summarizing the discussion: For airway clearance, comorbidities that compromise clearance include tracheobronchomalacia, airway compression/stenosis/hypoplasia, restrictive lung disease (neuromuscular, chest wall deformities, scoliosis), and vocal cord or diaphragmatic dysfunction/paralysis from esophageal or cardiac surgery.↗
Summaries Katherine gave as host · CHARGE Syndrome10 summaries
Aerodigestive Management of Pediatric Aspiration - FULL SHOW
▶Ep 2 · 0:16
host summaryKatherine Hart summarizing the discussion: Aspiration is defined as any solid or liquid matter passing below the vocal cords, though some define it as requiring pulmonary compromise in addition to passage below the cords.↗
▶Ep 2 · 0:39
host summaryKatherine Hart summarizing the discussion: Aspiration can be silent with no clinical indication, or obvious with coughing, choking, and sputtering.↗
▶Ep 2 · 1:51
host summaryKatherine Hart summarizing the discussion: Children with CHARGE syndrome have 80 to 90% prevalence of aspiration at some point in their lifetime and should be assumed to aspirate until proven otherwise.↗
▶Ep 2 · 2:01
host summaryKatherine Hart summarizing the discussion: Children with severe neurologic compromise regardless of etiology should be assumed to aspirate until demonstrated otherwise.↗
▶Ep 2 · 2:32
host summaryKatherine Hart summarizing the discussion: The clinical significance of aspiration depends on the quantity—small isolated events are usually cleared by host defenses (cough, mucociliary transport), while large or repeated events overcome host defenses.↗
▶Ep 2 · 3:06
host summaryKatherine Hart summarizing the discussion: A single aspiration event of caustic substance can have lifelong consequences.↗
▶Ep 2 · 5:02
host summaryKatherine Hart summarizing the discussion: Syndromes with significant swallowing dysfunction include CHARGE, Cri-du-chat, Möbius syndrome (cranial nerve abnormalities), and craniofacial defects like Pfeiffer, Crouzon, and Treacher Collins.↗
▶Ep 2 · 44:25
host summaryKatherine Hart summarizing the discussion: Lipid-laden macrophages are the most commonly used aspiration biomarker, with a lipid-laden macrophage index >90 or >20% of macrophages containing lipid suggesting aspiration.↗
▶Ep 2 · 48:08
host summaryKatherine Hart summarizing the discussion: Having a tracheostomy tube changes the dynamics of laryngeal elevation but most studies show it does not create aspiration.↗
▶Ep 2 · 1:00:11
host summaryKatherine Hart summarizing the discussion: For airway clearance, comorbidities that compromise clearance include tracheobronchomalacia, airway compression/stenosis/hypoplasia, restrictive lung disease (neuromuscular, chest wall deformities, scoliosis), and vocal cord or diaphragmatic dysfunction/paralysis from esophageal or cardiac surgery.↗