Volume and function of the operated kidney after nephron-sparing surgery for unilateral renal tumor
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In brief
In brief
Retrospective study of 12 children who underwent zero-ischemia nephron-sparing surgery for unilateral renal tumors demonstrates strong correlation between preserved kidney volume and function on DMSA scintigraphy. Patients retaining ≥40% of operated kidney function showed stable renal parameters during adolescent follow-up, supporting the viability of nephron-sparing approaches in pediatric renal oncology.
Written by the GCMD Library team from the article.
Aim
We sought to assess the magnitude of functional decline and the natural history of the operated kidney residual function after zero-ischemia nephron-sparing surgery (Z-NSS) in children with unilateral renal tumor (URT).
Patients and methods
50 children were treated for URT at our surgical unit between 1992 and 2016. Of these 12 who underwent Z-NSS were available for the current analysis. Operated kidney function was assessed by 99mTc-dimercapto-succinic acid (DMSA) renal scintigraphy. Operated kidney volume was assessed by renal ultrasonography.
Results
A positive correlation between split renal function and split renal volume was found (P = 0.001). The subset of patients with ≥40% preservation of operated kidney function/volume (OKF/V) had no-time dependent changes during adolescence. The subset of patients with 80% follow-up and all patients enrolled at same time point in disease.