The diagnostic value of magnetic resonance imaging in differentiating benign and malignant pediatric ovarian tumors
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Read the article on pubmed.ncbi.nlm.nih.gov ↗Article · Jan 2021 · 1 min read
In brief
In brief
This retrospective study of 30 pediatric patients demonstrates that MRI effectively differentiates benign from malignant ovarian tumors using specific imaging criteria including tumor size, contrast enhancement patterns, and margin characteristics. The findings support preoperative MRI as a valuable tool for surgical planning, particularly when fertility preservation is a priority in children and adolescents.
Written by the GCMD Library team from the article.
Background: The diagnostic workup of ovarian tumors in children and adolescents is challenging because preserving fertility, in addition to oncological safety, is of particular importance in this population. Therefore, a thorough preoperative assessment of ovarian tumors is required.
Objective: To investigate the diagnostic value of MR imaging in differentiating benign from malignant ovarian tumors in children and adolescents.
Materials and methods: We conducted a retrospective study of all children and adolescents age <18 years who underwent MR imaging of ovarian tumors during 2014-2019 at a pediatric specialty center. Two radiologists reviewed all MR imaging. We used pathology reports to define the histological diagnosis.
Results: We included 30 girls who underwent MR imaging for an ovarian tumor. Signs indicative for malignancy were tumors with a diameter ≥8 cm, with areas of contrast enhancement, irregular margins, extracapsular tumor growth, and ascites. All benign and malignant ovarian tumors were correctly identified by the radiologists.
Conclusion: The diagnostic utility of MR imaging in classifying ovarian tumors in children and adolescents as benign or malignant is promising and might aid in defining the indication for ovarian-sparing versus non-ovarian-sparing surgery. We recommend evaluating these tumors with MR imaging prior to deciding on surgical treatment.
DOI: 10.1007/s00247-020-04871-2