Recent Progress in Pediatric Soft Tissue Sarcoma Therapy
sciencedirect.com shows its articles on its own site.
Read the article on sciencedirect.com ↗Article · Dec 2019 · 1 min read
In brief
In brief
This review examines advances in pediatric soft tissue sarcoma management through cooperative group trials, emphasizing the critical role of surgical technique in balancing oncologic control with preservation of function. Despite limited progress in chemotherapy regimens, improved outcomes have resulted from refined multimodal approaches combining surgery, radiation, and systemic therapy.
Written by the GCMD Library team from the article.
Publication date: Available online 20 November 2019
Source: Seminars in Pediatric Surgery
Author(s): Timothy B. Lautz, Andrea Hayes-Jordan
Abstract
Soft tissue sarcomas of childhood are a heterogenous group of tumors with a wide spectrum of presentations and outcomes. Most patients require multimodal therapy with chemotherapy, surgery and/or radiation. Improved outcomes in recent decades have been achieved through improvements in the comprehensive care of these children through large cooperative group studies, even as little progress has been made in the standard chemotherapy backbone. A thorough understanding of the nuances of surgical therapy for these children is required to minimize both the risk of local failure and the possibility of loss of vital form or function.