Pediatric surgical oncology: a brief overview of where we have been and the challenges we face
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In brief
In brief
This review traces the evolution of pediatric solid tumor treatment, highlighting how cooperative groups enabled systematic multidisciplinary approaches that dramatically improved survival rates. The article emphasizes the surgeon's critical role in modern cancer care, the importance of molecular characterization in treatment planning, and growing attention to long-term effects like infertility as more children survive into adulthood.
Written by the GCMD Library team from the article.
Publication date: Available online 20 November 2019
Source: Seminars in Pediatric Surgery
Author(s): Daniel von Allmen
Abstract
The evolution of the treatment of pediatric solid tumors has been one of progressive improvements in survival. With the advent of pediatric cooperative groups, a systematic approach has brought integrated multidisciplinary care to childhood cancer patients. Improved medical regimens and advances in the basic understanding and characterization of molecular biology of individual tumors continues to bring new treatment options. As long term survival has improved, a greater appreciation of the late effects of treatment has led to increase awareness and intervention for things like infertility. The surgeon remains a critical member of the treatment team. Surgical treatment techniques continue to evolve and the role of surgery in each tumor type is continually redefined. It is incumbent on the treating surgeon to know the treatment guidelines for each case in order to provide the patient with the best opportunity for a successful outcome.